在 Malian 女人的人的免疫不全病毒和丙肝病毒感染的流行病学的侧面: 风险因素和不同的关联认领被引量：1

Epidemiological profiles of human immunodeficiency virus and hepatitis C virus infections in Malian women:Risk factors and relevance of disparities

在线阅读免费下载

收藏分享导出

摘要 AIM:To document the epidemiologic patterns and risk factors of human immunodeficiency virus(HIV)and hepatitis C virus(HCV)infections in Mali in order to develop prevention means for both diseases.METHODS:Two prospective studies were conducted in Bamako in 2009 among 1000 pregnant women(i.e.,young women)who consulted six reference health centers,and in 2010,among 231 older women who attended general practice in two hospitals.Antibody tests and molecular analysis(performed only for HCV)were used to quantify the frequencies of both infections.The data were collected from patients recruited through a questionnaire.Transmission risk factors of both diseases were identified by univariate and multivariate analysis.RESULTS:HCV seroprevalence was 0.2% for young and 6.5% for older women.HIV prevalence was similar in both populations(4.1% vs 6.1%).In older women,the analysis of risk factors highlighted an association between HCV infection and episodes of hospitalization(P 【 0.01).The study did not show an association between HIV infection and the variables such as hospitalization,transfusion,tattoo,dental care,and endoscopy.A significant decrease of HIV seroprevalence was detected in young women who used condoms for contraception more than for other purposes(P 【 0.01).By contrast,HIV seroprevalence was significantly increased in young women using condoms mainly to prevent sexual infections rather than for contraception(P 【 0.01).No HCV/HIV coinfection was detected in our study.CONCLUSION:Risk factors and epidemiologic data of HIV and HCV as well as the absence of co-infection strongly suggest epidemiological disparities between these diseases. AIM:To document the epidemiologic patterns and risk factors of human immunodeficiency virus(HIV)and hepatitis C virus(HCV)infections in Mali in order to develop prevention means for both diseases.METHODS:Two prospective studies were conducted in Bamako in 2009 among 1000 pregnant women(i.e.,young women)who consulted six reference health centers,and in 2010,among 231 older women who attended general practice in two hospitals.Antibody tests and molecular analysis(performed only for HCV)were used to quantify the frequencies of both infections.The data were collected from patients recruited through a questionnaire.Transmission risk factors of both diseases were identified by univariate and multivariate analysis.RESULTS:HCV seroprevalence was 0.2% for young and 6.5% for older women.HIV prevalence was similar in both populations(4.1% vs 6.1%).In older women,the analysis of risk factors highlighted an association between HCV infection and episodes of hospitalization(P < 0.01).The study did not show an association between HIV infection and the variables such as hospitalization,transfusion,tattoo,dental care,and endoscopy.A significant decrease of HIV seroprevalence was detected in young women who used condoms for contraception more than for other purposes(P < 0.01).By contrast,HIV seroprevalence was significantly increased in young women using condoms mainly to prevent sexual infections rather than for contraception(P < 0.01).No HCV/HIV coinfection was detected in our study.CONCLUSION:Risk factors and epidemiologic data of HIV and HCV as well as the absence of co-infection strongly suggest epidemiological disparities between these diseases.

作者 Nouhoum Bouare Andre Gothot Jean Delwaide Sebastien Bontems Dolores Vaira Laurence Seidel Paul Gerard Christiane Gerard Nouhoum Bouare,Andre Gothot,Sebastien Bontems,Dolores Vaira,Christiane Gerard,Department of Clinical Biology,Laboratory Hematology,Immuno-Hematology and AIDS Reference Laboratory B35,Centre Hospitalier Universitaire,Université de Liège,4000 Liège,Belgium Jean Delwaide,Department of Hepatology and Gastroenterology,Centre Hospitalier Universitaire,Université de Liège,4000 Liège,Belgium Laurence Seidel,Department of Public Health(Biostatistics),Centre Hospitalier Universitaire,Université de Liège,4000 Liège,Belgium Paul Gerard,Institute of Mathematics,Université de Liège,4000 Liège,Belgium

机构地区 Department of Clinical Biology Department of Hepatology and Gastroenterology Department of Public Health（Biostatistics） Institute of Mathematics

出处《世界肝病学杂志：英文版（电子版）》 2013年第4期196-205,共10页 World Journal of Hepatology

基金 Supported by The Belgian Technical Cooperation

关键词 Hepatitis C VIRUS Human IMMUNODEFICIENCY VIRUS EPIDEMIOLOGY Risk factors Women MALI BAMAKO Hepatitis C virus Human immunodeficiency virus Epidemiology Risk factors Women Mali Bamako

分类号 R512.91 [医药卫生—临床医学][医药卫生—内科学] R512.63 [医药卫生—临床医学][医药卫生—内科学]

引文网络
相关文献

参考文献33

1Nouhoum Bouare,Dolores Vaira,Andre Gothot,Jean Delwaide,Sebastien Bontems,Laurence Seidel,Paul Gerard,Christiane Gerard.在 Malian 女人和血清学的试金表演的二张人口的 HIV 和 HCV 感染的流行[J].世界肝病学杂志：英文版（电子版）,2012(12):365-373. 被引量：1
2Ross,RS,Viazov,S,Thorm?hlen,M,Bartz,L,Tamm,J,Rautenberg,P,Roggendorf,M,Deister,A.Risk of hepatitis C virus transmission from an infected gynecologist to patients: results of a 7-year retrospective investigation. Archives of Internal Medicine . 2002 被引量：1
3Benouda A,Boujdiya Z,Ahid S,Abouqal R,Adnaoui M.Prévalence de l’’infection par le virus de l’’hépatite-C au Ma- roc et évaluation des tests sérologiques de dépistage pour la prédiction de la virémie. Pathologie Biologie . 2009 被引量：2
4Serme AK,Ilboudo PD,Samandoulgou A,Simpore J,Bou- gouma A,Sombie AR.Portage du virus de l’’hépatite C chez les femmes enceintes et transmission mère-enfant à Ouaga- dougou,Burkina Faso. Santé publique: courte note n°2764, juin 2005. Bulletin de la Société de Pathologie Exotique . 2006 被引量：2
5Trépo C,Merle P,Zoulim F.Hépatites virales B et C. Col- lection Pathologie,sciences,formation. . 2006 被引量：2
6O’’Reilly JI,Ocama P,Opio CK,Alfred A,Paintsil E,Serem-ba E,Sofair AN.Risk Factors and Seroprevalence of Hepa- titis C among Patients Hospitalized at Mulago Hospital, Uganda. Journal of Tropical Meteorology . 2011 被引量：2
7Ndjomou J,Kupfer B,Kochan B,Zekeng L,Kaptue L,Matz B.Hepatitis C virus infection and genotypes among human immunodeficiency virus high-risk groups in Cameroon. Journal of Medical Virology . 2002 被引量：2
8Ndong-Atome GR,Makuwa M,Njouom R,Branger M,Brun-Vézinet F,Mahé A,Rousset D,Kazanji M.Hepatitis C virus prevalence and genetic diversity among pregnant women in Gabon,central Africa. BMC Infectious Diseases . 2008 被引量：2
9F Roudot-Thoraval,A Bastie,J-M Pawlotsky,D Dhumeaux.Epidemiological factors affecting the severity of hepatitis C virus-related disease: a French survey of 6,664 patients. Hepatology . 1997 被引量：1
10Deflandre J,,Cajot O,Brixko C,et al.Risk of transmission by heP-atitis C of endoseopes utilized in gastroenierology hospital service. Revue Medicale de Liege . 2001 被引量：1

二级参考文献40

1Gibb DM;Goodall RL;Dunn DT.Mother-to-child transmission of hepatitis C virus: evidence for preventable peripartum transmission,2000. 被引量：1
2Pawlotsky JM.Use and interpretation of virological tests for hepatitis C,2002(Suppl 1). 被引量：2
3Benhamou Y,Bochet M,Di Martino V,et al.Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients. The Multivirc Group. Hepatology . 1999 被引量：2
4Diarra A,Kouriba B,Baby M,Murphy E, et al.HIV, HCV, HBV and syphilis rate of positive donations among blood donations in Mali:lower rates among volunteer blood donors. Transfusion Clinique et Biologique . 2009 被引量：1
5Report on the global AIDS epidemic. http://www.unaids.org /en/KnowledgeCentre/HIVData/GlobalReport/2008/2008_Global_report.asp . 被引量：1
6Delwaide J,Bourgeois N,Colle I,et al.Risk factors for hepatitis C:past,present and future. Acta Gastro Enterologica Belgica . 2002 被引量：2
7Santiago ML,Range F,Keele BF,Li Y,Bailes E,Bibollet-Ruche F,Fruteau C,Noe R,Peeters M,Brookfield JF,Shaw GM,Sharp PM,Hahn BH.Simian immunodeficiency virus infection in free-ranging sooty mangabeys (Cercocebus atys atys)from the Tai Forest,Cote d‘lvoire:implications for the origin of epidemic human immunodeficiency virus type 2. Journal of Virology . 2005 被引量：1
8Ruggieri A,Argentini C,Rapicetta M, et al.Heterogeneity of hepatitis C virus genotype2variantsin West Central Africa (Guinea Conakry). Journal of General Virology . 1996 被引量：1
9Hladik W,Kataaha P,Mermin J,et al.Prevalence and screening costs of hepatitis C virus among Ugandan blood donors. Tropical Medicine and International Health . 2006 被引量：2
10Seremba E,Ocama P,Opio C K,et al.Poor performance ofhepatitis C antibody tests in hospital patients in Uganda. JMed Virol . 2010 被引量：1

共引文献1

1Nouhoum Bouare,Dolores Vaira,Andre Gothot,Jean Delwaide,Sebastien Bontems,Laurence Seidel,Paul Gerard,Christiane Gerard.在 Malian 女人和血清学的试金表演的二张人口的 HIV 和 HCV 感染的流行[J].世界肝病学杂志：英文版（电子版）,2012(12):365-373. 被引量：1

同被引文献19

1Flisiak R,Halota W,Horban A,et al.Prevalence and risk factors ofHCV infection in Poland. European Journal of Gastroenterology and Hepatology . 2011 被引量：1
2C Vandelli,F Renzo,L Romano,S Tisminetzky,M Palma,T Stroffolini,E Ventura,A Zanetti.Lack of evidence of sexual transmission of hepatitis C among monogamous couples: results of a 10-year prospective follow-up study. The American journal of Gastroenterology . 2004 被引量：1
3Quer,J,Murillo,P,Esteban,JI,Martell,M,Esteban,R,Guardia,J.Sexual transmission of hepatitis C virus from a patient with chronic disease to his sex partner after removal of an intrauterine device. Sexually Transmitted Diseases . 2003 被引量：1
4Halfon,P,Riflet,H,Renou,C,Quentin,Y,Cacoub,P.Molecular evidence of male-to-female sexual transmission of Hepatitis C virus after vaginal and anal intercourse. Journal of Clinical Microbiology . 2001 被引量：1
5AN Turner,AE Kock,A Meehan-Ritter.Many vaginal microbicide trial participants acknowledged they had misreported sensitive behavior in face-to-face interviews. Journal of Clinical Epidemiology . 2009 被引量：1
6Ippolito,G,Puro,V,De Carli,G.Italian Study Group on Occupational Risk of HIV Infection. The risk of occupational human immunodeficiency virus in health care workers. Archives of Internal Medicine . 1993 被引量：1
7Perz JF,Grytdal S,Beck S,Fireteanu AM,Poissant T,Rizzo E,Bornschlegel K,Thomas A,Balter S,Miller J,Klevens RM,Finelli L.Case-control study of hepatitis B and hepatitis C in older adults: Do healthcare exposures contribute to burden of new infections?. Hepatology . 2013 被引量：1
8Baha W,Foullous A,Dersi N,They-They TP,Alaoui KE,Nourichafi N,Oukkache B,Lazar F,Benjelloun S,Ennaji MM,Elmalki A,Mifdal H,Bennani A.Prevalence and risk factors of hepatitis B and C virus infections among the general population and blood donors in Morocco. BMC Public Health . 2013 被引量：1
9Spada E,Mele A,Mariano A,Zuccaro O,Tosti ME.Risk factors for and incidence of acute hepatitis C after the achievement of blood supply safety in Italy: results from the national surveillance system. Journal of Medical Virology . 2013 被引量：1
10Kim JY,Won JE,Jeong SH,Park SJ,Hwang SG,Kang SK,Bae SH,Kim YS,Lee HC.Acute hepatitis C in Korea: different modes of infection, high rate of spontaneous recovery, and low rate of seroconversion. Journal of Medical Virology . 2011 被引量：1