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颈椎终板结构的生物力学研究 被引量:24

Mechanical structural properties of the cervical endplates
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摘要 目的研究颈椎终板不同位点生物力学特性的分布规律。方法选用人体新鲜颈椎标本66椎,对终板平面上的20个特定测试点进行压缩试验,用直径2mm的半球形压头以0.03mm/s的速度垂直终板平面下压2 mm,由所得的压缩力-位移曲线计算最大压缩力及刚度,采用析因分析对实验数据进行统计处理。结果(1)颈椎各节段之间最大压缩力及刚度的差异有显著性(P<0.01),且由上而下呈逐渐减小趋势。终板矢状方向上各点之间最大压缩力及刚度的差异有显著性(P<0.01),且椎体后部是最大压缩力及刚度较大的区域;终板冠状方向上各点之间最大压缩力及刚度(除下终板最大压缩力外)的差异均无显著性(P>0.05)。(2)下颈椎相邻终板之间的最大压缩力及刚度的差异有显著性(P<0.05),下终板的最大压缩力及刚度比上终板大。矢状方向上相邻终板的最大压缩力差异有显著性(P<0.05),但冠状方向上差异无显著性(P>0.05);在矢状方向及冠状方向上相邻终板的刚度差异均无显著性(P>0.05)。结论颈椎上终板后部、下终板后外侧区是椎体力学强度最大的区域。在进行颈前路融合术时下颈椎较易发生塌陷,且塌陷多发生于颈椎上终板平面。 Objective To study the distribution of the biomechanical properti es of the cervical endplates. Methods Indentation tests perpendicular to the end plate surface were performed at 20 standardized test sites in 66 cervical endpla tes of intact human vertebrae (C2-C7), using a 2 mm-diameter, hemispherical inde nter with a test rate of 0.03 mm/s to a depth of 2 mm. The failure load and stif fness at each test site were determined by the load-displacement curves. Factori al analyses were used to analyze the resulting data. Results 1) The failure loa d and stiffness varied significantly among the cervical levels (P<0.01). The sup erior cervical endplates were found to be stronger than the inferior cervical en dplates. Both the failure load and stiffness varied significantly among the test sites in the sagittal direction across the endplate surface (P<0.01). The poste rior test sites were stronger and stiffer than the other sites. However, there w ere no difference (except the failure load of the inferior endplate) among the t est sites in the coronal direction (P > 0.05). 2) There were no difference in t he failure load and stiffness between the superior and the inferior endplate at the adjacent C3,4 and C4,5 (P>0.05), however, significant differences existed at the adjacent C5,6 and C6,7 (P<0.01). The inferior endplate was stronger and sti ffer than the superior endplate. There was no difference in the failure load, bu t a significant difference in the stiffness at the adjacent C2,3 cervical endpla tes. The failure load varied among the test sites in the sagittal direction acro ss the adjacent endplate surface (P<0.05), but did not vary in the coronal direc tion (P>0.05). No differences were found in the stiffness at both the sagittal a nd coronal directions. Conclusion The posterior regions of the superior endplate and the posterolateral regions of the inferior endplate are the stronger and st iffer regions across the endplate surface comparing with other regions. It is ea sier to have the subsidence syndrome complic
作者 李鉴轶 朱青安 原林 赵卫东 林荔军 黄文华 吴旸 LI J ian-yi, ZHU Qing-an, YUAN Lin, et al. Key Lab of Medical Biomechanics of PLA, th e First Military Medical University, Guangzhou 510515, China
出处 《中华骨科杂志》 CAS CSCD 北大核心 2004年第2期 108-112,共5页 Chinese Journal of Orthopaedics
基金 广东省科技攻关项目
关键词 颈椎终板结构 生物力学 压缩试验 抗压强度 Cervical vertebrae Compressive strength Spinal fusion
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