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广东省五华县流行性乙型脑炎流行特征分析 预览 被引量:1

Epidemiological Characteristics of Encephalitis B in Wuhua County of Guangdong Province
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摘要 目的分析五华县流行性乙型脑炎的流行病学、临床表现、实验室检查等特点.方法对五华县2003年5-6月份出现的流行性乙型脑炎病人的流行病学资料及临床资料进行分析.结果患者年龄从8个月至11岁,流行从5月27日开始至6月30日止,乙脑病例分布于22个镇,没有家庭聚集现象.患者95.5%无疫苗接种史.症状均有发热,抽搐、昏迷.体征颈强直占86.4%,克氏征阳性63.6%、布氏征阳性68.2%.血象白细胞总数平均16.8×109/L,中性粒细胞平均8.5×109/L.患者早期血清检测乙脑IgM抗体阳性率46.2%.经综合治疗后死亡2例,病死率4.5%.结论乙型脑炎流行具严格的季节性和年龄特征,呈高度散发.患者居住卫生条件差、传媒蚊虫多、山区防疫工作有漏洞、免疫接种率低,是引起流行主要因素.迟报的原因为临床医生的误诊.因此应重视对流行病学资料的分析,提高诊断水平和监测能力,以便尽早对传染病早期采取预防控制措施. Objective To determine the epidemiological characteristic,clinical feature,laboratory examination of encephalitis B in Wuhua county Methods The epidemiological data and clinical feature of encephalitis B cases were analyzed. Results The patients age range was 8 months to 11 years old, and the epidemic period was from May 27 to June 30. The cases of Encephalitis B distributed over 22 towns with no family gathering. 99.5% of cases had no history of vaccination and all of the cases had fever, twitch and coma. There were 86.4% of patients with stiff neek, 63.6% with klinefelter's syndrome, and 68.2% with Brudzinski' syndrem. Leucocyte total average was 16.8×10 9/L, and neuter granule cell average was 8.5×10 9/L. The IgM antibody positive rate of Encephalitis B was 46.2% in the early serum examination. After comprehensive treatment, 2 patients died with the death rate 4.5%. Conclusion The prevalence of Encephalitis B presented a very strict season and age characteristics. The poor living condition, massive media insects, the shortage in epidemic prevention in rough area, and low vaccination rate were main factors. It was improtant to emphasis the epidemiological analysis, to develop the diagnosis and inspect ability, and to control the disease prevalence of as early as possible.
作者 廖云开 卢水英 邹兴梅 孔祥钦 张丽丽 LIAO Yunkai,et al (Center for Disease Contorl and Prevention of Meizhou City, Guangdong Meizhou 514021)
出处 《疾病监测》 CAS 2004年第7期 245-247,共3页 Disease Surveillance
关键词 患者 流行性乙型脑炎 流行病学资料 流行特征分析 阳性 乙脑 早期 防疫工作 五华县 卫生条件 Encephalitis B Epidemiology Characteristics Epidemiological Data
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