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纤维蛋白原水平在恶性肿瘤诊治中的临床意义 预览 被引量:7

Clinical significance of fibrinogen in diagnosis and treatment in cancer patients
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摘要 目的:检测恶性肿瘤患者血浆纤维蛋白原(FIB)含量,评价其在恶性肿瘤患者诊治中的临床意义.方法:采用BE凝血仪对166例晚期恶性肿瘤患者化疗前后的血浆进行FIB测定.结果:晚期恶性肿瘤患者FIB水平[(3.65±1.11)g/L]显著高于早期恶性肿瘤患者FIB水平[(2.98±0.81)g/L];化疗好转的晚期恶性肿瘤患者的FIB水平[(2.59±0.65)g/L]较治疗前下降;而复发转移的晚期恶性肿瘤患者FIB水平[(3.97±1.10)g/L]再次升高.结论:FIB在诊断监测晚期恶性肿瘤化疗疗效及评估预后方面对临床有一定的指导意义. Purpose:To observe the clinical value of plas ma fibrinogen (FIB) content involved in 166 advanced cancer patients in the the d iagnosis and treatment. Methods:BE automated coagulation analyzer was used in monitorin g FIB in the patients. Results:The FIB content was significantly higher in patients w ith advanced malignant diseases than in early patients .Significant decrease was observed after treatment, then became elevated again when there was recurrence or metastasis. Conclusions:Assessment of FIB can help not only to diagnose pat ients with advanced malignant diseases, but also to evaluate the therapeutic eff ect and prognosis.
作者 林懿 林英城 林文照 王鸿彪 林穗玲 曾德 霍霞 LIN Yi,LIN Ying-cheng, LIN Wen-zhao,et,al (Department of M edical Oncology ,Shantou Tumor Hospital. Shantou University Medical College, Sha ntou Guangdong 515031,China)
出处 《中国癌症杂志》 CAS CSCD 2004年第6期 521-522,526,共3页 China Oncology
关键词 恶性肿瘤 血浆纤维蛋白原 诊治 malignant neoplasms blood plasma fibrinogen diagnosis and treatment
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  • 1[1]Voland C,Serre CM, Delmas P. Platelet-osteosarcoma cell Interaction is mediated through a specific fibrinogen-binding sequence located within the N-terminal domain of thrombospondin 1 [J]. J Bone Miner Res, 2000,15(2): 361-368. 被引量:1
  • 2徐光炜.临床肿瘤学[M].沈阳:辽宁教育出版社,1999.1555-1630. 被引量:23
  • 3王振义等主编..血栓与止血基础理论与临床[M],1996:683.
  • 4银正民主编..临床肿瘤急症学[M],2000:672.
  • 5[5]汤钊湭现代肿瘤学[M].上海:上海医科大学出版社,2000:240 被引量:1
  • 6[6]Palumbo JS, Potter JM, Kaplan LS et al. Spontaneous hematogenous and lymphatic metastasis ,but not primary tumor growth or angiogenesis, is diminished in fibrinogen-deficient mice[J]. Cancer Res, 2002, 62(23): 6966-6972. 被引量:1
  • 7[7]Palumbo JS, Kombrinck KW, Drew AF, et al, Fibrinogen is an important determinant of the metastatic potential of circulating tumor cells[J]. Blood, 2000,96(10): 3302-3309. 被引量:1
  • 8刘秀巧,王淑娟,等.恶性肿瘤与高纤维蛋白原血症[J].中华肿瘤杂志,2002,24(1):51-52. 被引量:85

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