To understand the basis for the prevalence of serum antibodies to West Nile virus (WNV) and to investigate the immuno-cross reaction between WNV and Japanese encephalitis virus (JEV) in populations, 347 adult serum specimens were collected from recruits, and the IgG antibodies to WNV were determined by means of the indirect immunofluorescence assay (IFA)developed in our laboratory. It was found that the prevalence rates of serum antibody to WNV and JEV were 3.2% (11/347) and (5.7%) (14/244) respectively. Among the 244 specimens in which examinations were performed simultaneously for both WNV and JEV,3 were found to be positive for both antibodies, and the percentages of positive samples for WNV or JEV were 60% (3/5) or 21% (3/14) respectively. It is concluded that less immunity against WNV exists in population examined and the value of cross immunity with JEV antibodies to WNV may be limited.
Chinese Journal of Zoonoses
West Nile virus
Japanese encephalitis virus
indirect immunofluorescence assay