he effects of the estradiol control delivery patchmade in China on the main manifestation in the 176cases of ovarian failure patient were evaluated with theimprovement of their symptoms, the changes of serumlevels of LH, FSH, E2, the vaginal exfoliated cytologicmaturation index (MI) and the histological alterationof endometrium.The results indicated that the six main symptomsincluding hectic fever, sweating, vaginal dry andhardgoing, dizziness, emotioned lability and insom-nia were improved significantly and progressively withprolongation of the treatment. The effective rates were97.9%, 97.5%, 93.7%, 77.0%, 76.2%, 75.0%respectively form hectic fever to insomnia. Theinhibitory effects on serum LH. FSH levels occurredon the 10th day of the treatment. The MI increasedwithin whole course and the serum estradiol level ele-vated slightly and stably. There were no significantendometrial proliferation caused by the patch.
Chinese Journal of Obstetrics and Gynecology