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六种抗菌药物体外对解脲支原体与人型支原体的抗菌作用 被引量:56

In Vitro Antibacterial Activities of 6 Antimicrobial Agents Against Ureaplasma Urealyticum and Mycoplasma Hominis
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摘要 采用琼脂对倍稀释方法,测定了6种国产抗蓖药物对30株解脲支原体、30株人型支原体体外抗菌作用效果,结果显示,乙酰螺旋霉素,氟酸和强力霉素有较可的抗Uu与Mh作用。乙酰螺旋霉素抗Uu的MIC50与MIC90为0.25mg/L与1mg/L,抗Mh为0.5mg/L与1mg/L。氟哌酸抗Uu与Mh作用相同,MIC50与MIC90为0.5mg/L与1mg/L.强力霉素抗Uu的MIC50与MIC90为0.5m In this report,in vitro antibacterial activities of 6 antimicrobial agents against 30 strains of Urea plasma urealyticum (Un), 30 strains of Mycoplasma hominis (Mh)were determined using agar dilution method. The results indicated that acetylspiramycin,norfloxacin and doxycycline are highly active against Uu and Mh. Acetylspiramycin is active against Uu, MIC50 0. 25mg/L, and MIC90 1mg/L, against Mh, MIC50 0. 5mg/L and MIC90 1mg/L. Norfloxacin is equally ac- tive against Un and Mh, MICS, 0.5mg/L and MIC50 1mg/L. Doxycycline is active against Uu and Mh, for Un MIC50 is 0. 5mg/L and MIC90 1mg/L,and for Mh MIC50 is 0. 25 and MIC90 2mg/L.Mh is resistant to erythromycin (MIC50 60mg/L and MIC90 128mg/L). Six strains of Un and 4 strains of Mh are highly resis- tant to tetracycline (MIC50 64 to 128mg/L and MIC90 16 to 32mg/L)and yet still sensitive to the other an- timicrobial agents. Berberine is equally active against Uu and Mh (MIC50 4mg/L and MIC90, 8mg/L) and is effective for the tetracycline resistant strains of Uu and Mh.
作者 吴移谋 余敏君 WU Yi-Mou; YU Min-Jun; LIU Teng-Fei, et al. (Department of Microbiology, Hengyang Medical College,Hu-nan 421001)
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 1994年第3期 134-135,共2页 Chinese Journal of Dermatology
关键词 解脲枝原体 人型枝原体 抗生素 Ureaplasma urealyticum Mycoplasma hominis Antibiotics
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参考文献2

  • 1吴移谋,中华皮肤科杂志,1991年,24卷,251页 被引量:1
  • 2吴移谋,中华医学检验杂志,1991年,14卷,157页 被引量:1

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