We studied the effects of pulsed electromagnetic fields (PEF)on articular cartilage defects in 80 Wistar rats. The results showed that the degree of passive motion of the PEF group was significantly greater than the control one at 14 days(P<0. 05). This difference was even more significant at 28 and 56 days(P<0. 001). Histological examination showed that in the PEF group there was evidence of minor inflammation around the defects. In addition chondrocytes in the PEF rats appeared earlier than in the control group. They matured faster and aligned themselves earlier. It is possible that PEF may enhance the differentiation of the subchondral elements such as mes-enchymal precursor cells.
The Journal of Bone and Joint Injury