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慢肝汤联合复方甘草酸苷治疗慢性乙型肝炎的疗效观察 预览 被引量:1

Clinical Therapeutic Observation of Man'gan Decoction Plus Compound Glycyrrhizin in the Treatment of Chronic Type B Hepatitis
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摘要 目的:观察慢肝汤联合复方甘草酸苷治疗慢性乙型肝炎的疗效.方法:将46例中度慢性乙型肝炎患者随机均分为治疗组和对照组,治疗组应用自拟慢肝汤治疗6mo,同时应用复方甘草酸苷治疗3mo;对照组应用甘草酸二铵、维生素、复方氨基酸注射液等常规治疗6mo.结果:治疗结束时治疗组肝功能及肝纤维化指标水平均显著好于对照组(P<0.05);治疗结束时治疗组HBV-DNA阴转10例,HBeAg阴转9例,ALT复常/HBV-DNA和HBeAg阴转9例,均显著好于对照组(P<0.05).结论:慢肝汤联合复方甘草酸苷治疗慢性乙型肝炎有较好的疗效. OBJECTIVE: To observe the Therapeutic effect of Man'gan decoction plus compound glycyrrhizin in the treatment of chronic type B hepatitis. METHODS: 46 patients with chronic hepatitis B were randomly divided into treatment group and control group. The treatment group was treated with self-planned Man'gan decoction for 6mo plus compound glycyrrhizin for 3mo; the control group received 6 months' conventional therapy-diammonium glycyrrhizinate, vitamin and amino acid compound injection, etc. RESULTS: At the end of treatment, the hepatic function and hepatic fibrosis index levels of the treatment group were superior to the control group(P〈0.05) and in which group 10 cases whose HBV-DNA turned negative and 9 cases whose HBeAg turned negative; there were 9 cases whose ALT recovered to normal level and HBV-DNA and HBeAg turned negative in this group, which were also superior to the control group(P〈0.05). CONCLUSION:The therapy of Man'gan decoction plus compound glycyrrhizin has a good therapeutic effect in the treatment of chronic type B hepatitis.
作者 尚建中 Shang JianZhong
出处 《中国药房》 CAS CSCD 北大核心 2005年第15期 1168-1170,共3页 China Pharmacy
关键词 慢性乙型肝炎 乙型肝炎病毒 慢肝汤 复方甘草酸苷 Chronic type B hepatitis HB virus Man'gan decoction Compound glycyrrhizin
作者简介 副主任医师。研究方向:感染病的临床研究。电话:0391-3929470
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