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良性肿瘤与恶性肿瘤患者血液流变学及血凝变化的比较研究 预览 被引量:10

Comparison Research on Hemorheology and Blood Concretion Changes in Patients with Benign and Malignant Tumors
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摘要 目的比较良恶性肿瘤患者的血液流变学及血凝的变化.方法观察50例健康人,100例肿瘤患者(其中50例为良性,50例为恶性),对其血液流变学指标及血小板计数、血小板聚集率指标进行比较.结果良性肿瘤患者全血黏度、血浆黏度、纤维蛋白原、血沉、红细胞压积、红细胞聚集指数、血小板计数、血小板聚集率等与健康人相比无显著性差异(P>0.05),恶性肿瘤患者上述指标均显著高于良性患者及健康人(P<0.01或P<0.05).结论恶性肿瘤患者存在血液高黏、高凝、血细胞高聚状态.血液流变学及血凝的异常可能会促进肿瘤发生和发展. Objective To compare the changes of hemorheology and blood concretion status in patients with benign and malignant tumors. Methods Hemorheological indicators,platelet count ,and platelet aggregation rate were measured in 50 healthy persons and 100 tumor sufferers (50 among those examples with benign tumors and 50 with malignant tumors) .Results In patients with benign tumors,whole blood viscosity ratio,plasma viscosity ratio, plasma fibrinogen, erythrocyte sedimentation rate, erythrocyte hematocrit, erythrocyte aggregation index, platelet count, and platelet aggregation rate were compared with that of the healthy ones to have no obvious differences( P 〉 0.05), but in patients with malignant tumors, the abovementioned indexes showed significantly differences from those both in the healthy ones and the patients with benign tumors( P 〈 0.01 or P 〈 0.05). Conclusions Hyperviscosity, hypercoagulability and hyperdetention were presented in the blood of patients with maligmant tumors. The abnormal changes in hemorheology and the blood concretion may promote the occurrences of the blood ways' transfer with tumors.
作者 田敏 邢鑫 刘洋 Tian Min;Xing Xin;Liu Yang
出处 《河南肿瘤学杂志》 2005年第5期 313-315,共3页 Henan Journal of Oncology
关键词 血液流变学 血凝 良性肿瘤 恶性肿瘤 hemorheology blood concretion benign tumors malignant tumors
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