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埃可19型肠道病毒性脑炎102例的流行病学及临床报告 预览 被引量:5

THE EPIDEMIOLOGY AND CLINICAL REPORT FOR 102 CASES OF ECHO 19 ENTERIC VIRAL ENCEPHALITIS
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摘要 目的:探讨埃可19型肠道病毒性脑炎的流行病学及临床特点.方法:对2004年5-7月该病流行期间入院的102例患儿进行流行病学调查及临床资料分析;28份患儿的脑脊液标本,送省疾病控制中心实验室,用细胞培养的方法分离病毒,阳性株经中和试验及分子生物学的方法鉴定和分型.结果:病例散发分布于龙岩市4个街道办事处、11个乡镇及周边7个县,流行季节为5~7月份,6~12岁的学龄儿童,特别是男童为易感人群;临床表现以发热和神经系统症状为主,小于6岁婴幼儿出现咳嗽、腹泻、抽搐较年长多,脑脊液压力增高,细胞数及蛋白正常或轻度升高,糖及氯化物正常;28份脑脊液共分离出埃可19型肠道病毒16株.结论:该市流行的小儿病毒性脑炎由埃可19型肠道病毒引起,其临床症状典型,但以轻症病人为主,治疗顺利,预后良好. Objective: To find out the character of epidemiology and clinical stigma for 102 cases of Echo 19 enteric viral encephalitis.Methods: Epidemiology research and clinic analyse of 102 cases of enteric viral encephalitis was conducted during epidemic period from May to July, 2004 in our hosptial. 28 samples of cerebrospinal fluid from patients were isolated by cell culture in center laboratory of Fujian CDC, Neutralization test and Molecular biology survey were applied to evaluate and type.Results: It showed that 102 cases distribute over four populated districts, 11 small towns in Longyan city and 7 counties around it, epidemic occurs in May to July, 6 to 12 years old sehcol - children especially male were more susceptible. Main symptom was febrile and nervous system symptom. Cough, diarrhoea and tic were more contain in those cases were under 6 years old. The pressure increased in spinal fluid and the number of cells and the content of protein in spinal fluid were normal or increased slighly, the content of sugar and chloride were normal. 16 strait Echo 19 enterovirus were isolated from 28 samples. Conclusion: The viral encephalitis that epidemic in Longyan was caused by Echo 19 enterovirus, they have typical symptom and eusemia.
作者 谢辉 张月花 钟卫东 李仙花 吴炽勇 Xie Hui;Zhang YueHua;Zhong WeiDong;Li XianHua;Wu ChiYong
出处 《现代预防医学》 CAS 北大核心 2005年第9期 1111-1112,1114,共3页 Modern Preventive Medicine
关键词 埃可19型肠道病毒 病毒性脑炎 流行病学 临床表现 Echo 19 enterovirus Viral encephalitis Epidemiology Clinical situation
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