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布洛芬在流行性乙型脑炎患者的降温疗效观察 预览 被引量:3

Antithermic Effects of Ibuprofen on Japanese Encephalitis Patients
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摘要 目的观察流行性乙型脑炎患者用布洛芬降温治疗的疗效及安全性。方法药物降温组胃管注入布洛芬制剂(美林口服液),按年龄剂量每4h一次,至体温稳定在38℃以下,其他治疗与对照组相同。结果治疗后1h.2h、4h、12h、24h、48h两组病例体温对比有显著差异(P〈0.01),治疗组在治疗48h内降温效果较对照组更好;治疗组神志异常恢复更快(P〈0.05);两组病人均未发生严重副作用。结论流行性乙型脑炎患者用布洛芬降温较单纯物理降温效果更佳,病情恢复更快,并且安全性高。 Objective To evaluate the antithermic effect of Ibuprofen on patients with Japanese encephalitis. Methods The observation group : Age-appropriate dosage of Ibuprofen was infused into the patients through the stomach tube every 4 hours till the body temperature is under 38℃. Other treatments are the same as that of the control group. Results A significant reduction (P〈0.01) in fever was observed in patients after 1,2,4,12, and 24 hours of treatment. Within 48 hours, the effect of fever reduction on the treatment group was more apparent than the control group(P〈0.05 ). There was no serious side effect on the patients in these two groups. Conclusion The antithemic effect of Ibuprofen was evaluated in this study. It is safe and effective for the patients with Japanese encephalitis.
作者 何日东 庞增 张木春 HE Ri-dong, PANG Zeng, ZHAN Mu-chun (Department of Infectious Disease, Zhanjiang Central People's Hasp ital , Guangdong , Zhanjiang 52403 7, China)
出处 《热带医学杂志》 CAS 2006年第7期 837-838,共2页 Journal Of Tropical Medicine
关键词 流行性乙型脑炎 发热 布洛芬 Japanese encephalitis pyrexia Ibuprofen
作者简介 何日东(1964-),男,副主任医师,主要从事感染性疾病临床诊治工作。
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