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“蒙特利尔认知评估量表”在轻度认知损伤患者筛查中的应用 被引量:146

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摘要 老年性痴呆(Alzheimer's disease,AD)的发病率随着世界人口老龄化的加剧而迅速攀升。由于中晚期AD的治疗效果不佳,有关研究的注意力已经转向如何识别其智能减退的早期症状,以期预防、减缓甚至逆转痴呆的脑功能损害。轻度认知损伤(mild cognitive impairment,MCI)是发生在老年人群的认知功能减退综合征。据美国神经病学研究所(ANN)报道,每年MCI患者进展为AD的发生率达6%~25%,因而MCI患者是AD的高危人群。如能找到检测MCI的特异和敏感的筛查指标,建立客观、准确、便捷的早期诊断方法,及时干预防止其演化为AD,则可极大地减少AD的危害,减轻患者家庭的巨大精神压力和经济负担。因此,对于MCI患者的有效筛查是当前国内外认知领域研究的重点。
作者 王炜 王鲁宁
出处 《中华内科杂志》 CAS CSCD 北大核心 2007年第5期 414-416,共3页 Chinese Journal of Internal Medicine
基金 军队“十一五”重要课题基金(01Z037)
作者简介 通信作者:王炜,Email:wangwei301@hotmail.com
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参考文献20

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