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抗生素的环境残留、生态毒性及抗性基因污染 预览 被引量:170

Environmental Residues and Ecotoxicity of Antibiotics and Their Resistance Gene Pollution:A Review
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摘要 抗生素的环境污染与生态毒害问题近年来引起了极大的关注.在总结国内外相关研究基础上,对环境中几种典型抗生素(四环素、土霉素、氯四环素和磺胺类等)的污染源以及在水和土壤环境中的残留与污染水平进行了分析;对抗生素的污染生态毒性最新研究进展给予了评述;对抗生素抗性基因在环境中可能的暴露途径进行了探讨,指出应将抗生素抗性基因作为一类新的环境污染物.鉴于我国抗生素污染的严峻事实,建议应从国家层面上尽快开展有关抗生素环境污染和生态毒害机理的系统研究.  More and more attention has been paid to the challenging issue on environmental contamination and ecological poisons of antibiotics in recent years. Pollution sources of some typical antibiotics including tetracycline(TC), oxytetracycline(OTC), chlortetracycline(CTC)and sulfonamides and their residues and contaminant levels in water and soil environment were analyzed. In particular, the newly progress in pollution ecotoxicity of antibiotics were reviewed. Due to the residual toxicity of antibiotics, antibiotics resistance genes(ARGs)were suggested as one of the emerging pollutants and more concerns should be paid to the type of pollutants. The potential exposure pathways of ARGs were also discussed. In view of the austere pollution facts of antibiotics, we offer a proposal that a systematic research on environmental pollution and ecotoxicological mechanisms of antibiotics should be carried out as a national reconnaissance.
作者 周启星 罗义 王美娥 ZHOU Qi-xing,LUO Yi,WANG Mei-e( 1. College of Environmental Sciences and Engineering,Nankai University,Tianjin 300071;2. Key Laboratory of Terrestrial Ecological Process,Institute of Applied Ecology,Chinese Academy of Sciences,Shenyang 110016)
出处 《生态毒理学报》 CAS 2007年第3期 243-251,共9页 Asian Journal of Ecotoxicology
基金 国家“973”项目(No.2004CB418503) 国家自然科学基金项目(No.20777041)
关键词 抗生素 土壤 水环境 抗生素抗性基因(ARGs) 生态毒理学 生态风险 antibiotics soil water environment antibiotics resistance genes(ARGs) ecotoxicology ecological risk
作者简介 通讯作者(Corresponding author),周启星(1963-),男,博士,教授,博士生导师.教育部长江学者特聘教授,中国科学院“引进国外杰出人才”百人计划入选者.现任南开大学环境科学与工程学院院长、中国科学院陆地生态过程重点实验室主任.主要从事土壤生态毒理与污染生态化学、污染土壤生态修复与污染控制生态学以及城镇环境工程等方面的研究.E—mail:Zhouqx@nankai.edu.cn.
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