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凝血纤溶系统因子与肺癌预后的相关性研究

Prognostic significance of blood coagulation and fibrinolysis disorders in lung cancer
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摘要 肿瘤患者出现凝血、纤溶系统异常很常见,特别在肺癌患者更为明显。这些异常不仅引起血栓、弥漫性血管内凝血(DIC)等直接危害患者生命,而且在肿瘤的生长、侵袭和转移过程中起重要作用。血小板、促凝物质、D-二聚体、uPA系统因子、抗凝血酶(AT)Ⅲ及凝血酶-抗凝血酶Ⅲ复合物(TAT)等凝血、纤溶系统因子对患者病情及预后具有明显作用。 Coagulation and fibrinolysis disorders are very common in cancer patients, especially in lung cancer patients. These disorders not only cause thrombosis and diffuse intravascular coagulation, but also play a critical role in cancer growth, invasion and metastasis. Coagulation and fibrindysis system factors, such as platelet, procoagulant, D-dimer, uPA factors, AT Ⅲ and TAT, have obvious prognostic significance in lung cancer.
作者 郑华(综述) 王敬萍 李宝兰(审校) ZHENG Hua (General Department, Beijing Chest Hospital, Beijing 101149, China)
出处 《国际肿瘤学杂志》 CAS 2008年第9期694-697,共4页 Journal of International Oncology
关键词 肺肿瘤 血液凝固 纤维蛋白溶解 预后 Lung neoplasms Blood coagulation Fibrinolysis Prognosis
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参考文献22

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