Objective To study the relationship between ABO blood groups and cancer of stomach in Hans of Guangdong province and invest the role of the blood-group substance during the occurrence of the cancer. Methods ABO blood group distribution of 251 patients with gastric cancer and 235 healthy controls were enrolled in our study and the relation between two groups was analyzed. Furthermore, the Relative Rise （RR） of each blood antigen was calculated. Results The distribution of ABO blood groups in patients versus control groups was A in 36.65% （versus 25.96% （0.01〈P〈 0.05）, O in 22.71% versus 30.64%（0.01〈P〈0.05）, B in 31.47% versus 35.32%（P〉0.05）,AB in 9.17% versus 8.08%（P〉0.05）. The frequency of gastric cancer in A group was higher than those non-A groups, and the RR was 1.65 in A and 0.66 in O, 0.84 in B and 1.15 in AB. Conclusion There is obvious relationship between stomach cancer and ABO blood groups in Hans of Guangdong province. The blood antigen A is a vital risk factor during the form of stomach cancer.
Lingnan Modern Clinics in Surgery
ABO blood groups
Cancer of stomach