期刊文献+

江苏省儿童乙肝流行及疫苗接种状况调查 被引量:19

Investigation on epidemic situation of hepatitis B virus and vaccination among children in Jiangsu province
分享 导出
摘要 目的分析江苏省儿童乙肝疫苗接种和乙肝流行现状,评价乙肝疫苗纳入儿童免疫规划管理后的效果。方法采用多阶段分层整群随机抽样方法,调查城乡监测点1-14岁常住儿童1894名,进行乙肝疫苗接种情况以及乙肝感染主要危险因素问卷调查;采集静脉血,用酶联免疫法(ELISA)检测血清中乙肝病毒表面抗原(HBsAg)乙肝病毒表面抗体(抗-HBs)、乙肝病毒核心抗体(抗-HBc)。结果江苏省1—14岁城市儿童乙肝疫苗接种率、首针及时接种率分别为97.13%,78.43%,农村儿童分别为95.15%,57.96%;1~14岁儿童HBsAg阳性率、抗-HBs阳性率、抗-HBc阳性率、乙肝病毒(HBV)感染流行率经标化调整后分别为1.10%,70.02%,3.40%,5.53%。结论江苏省乙肝疫苗纳入免疫规划效果显著,5岁以下儿童HBsAg阳性率已降至1%以下,乙肝疫苗接种率和首针及时率逐年提高。 Objective To analyze the situation of hepatitis B virus(HBV) infection and vaccination and to evaluate the immunization effects after hepatitis B vaccine involved in the expanded program on immunization(EPI). Methods A survey for 1 894 children aged 1 - 14 years old was carded out in national surveillance sites using multistage cluster randomized sampling method. Every child' s hepatitis B immunization history and main risk factors were investigated through questionnaire. Venous blood samples were collected and tested for HBsAg, anti-HBs and anti-HBc by ELISA method. Results Among the children the rates of hepatitis B vaccine inoculation and timeliness of birth dose in urban area were 97. 13% and 78. 43% ,but the rates in rural area were 95. 15% and 57. 96% ,respectively. The age standardized positive rates of HBsAg, anti-HBs,anti-HBc and HBV infection were 1.10% ,70. 02% ,3.40% and 5.53% ,respectively. Conclusion Achievement in hepatitis B control and prevention has been made in Jiangsu province since hepatitis B vaccine was brought into EPI. The positive rate of HBsAg was below 1% for children aged less than 5 years old. The rates of hepatitis B vaccine inoculation and timeliness of birth dose were increased.
作者 汪志国 马福宝 汤奋扬 陶红 黄红玉 周羚 羊海涛 葛均 WANG Zhi-guo , MA Fu-bao , TANG Fen-yang , et al. (Jiangsu Provincial Center for Disease Control and Prevention (Nanjing 210009, China) )
出处 《中国公共卫生》 CAS CSCD 北大核心 2009年第4期483-485,共3页 Chinese Journal of Public Health
基金 卫生部2006年全国人群乙肝等有关疾病血清学调查(卫疾控发[2006]353号) 感谢江苏省浦口区、吴中区、张家港市、响水县、金湖县、云龙区疾病预防控制中心对本研究的大力支持!
关键词 乙肝疫苗 乙型肝炎表面抗原 接种率 儿童 hepatitis B vaccine HBsAg inoculation rate children
作者简介 汪志国(1977-),男,安徽东至人,主管医师,硕士,主要从事免疫规划针对疾病防制工作。
  • 相关文献

参考文献5

二级参考文献19

共引文献970

同被引文献191

引证文献19

二级引证文献86

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈