目的：探讨短期静脉营养对慢性阻塞性肺病（ＣＯＰＤ）并发营养不良（ＭＮＣＯＰＤ）能量代谢和运动耐量的影响。 方法：ＣＯＰＤ缓解期病人３０例，按治疗方案分为两组：Ａ组（营养膳食＋静脉营养组）１５例，Ｂ组（营养膳食组）１５例。静脉营养采用华瑞公司生产的英脱利匹特和凡命等。治疗前及治疗１周后作营养评价、静息能量消耗（ＲＥＥ）、运动试验和呼吸肌张力测定。 结果：两组均存在蛋白质－能量型营养不良，治疗后Ａ组营
Objectives:The study was done to investigate the effects of short term intravenous nutritional supply on energy metabolism and exercise intolerance in chronic obstructive pulmonary disease associated with malnutrition(MN COPD). Methods:According to treatment methods,30 stable MN COPD patients were divided into two groups:Group A had 15 cases treated with nutritional food and intravenous nutritional supply and Group B had 15 cases treated only with nutritional food.Intravenous nutritional supply was accomplished with Intralipid and Vamin produced by Sino Swed Pharmaceutical Corp.Ltd.Rest energy expenditure(REE),exercise test and respiratory muscle strength were measured before and 1 week after the treatment. Results:Both of the groups had malnutrition of protein energy type.In Group A,nutritional parameters were significantly improved,and REE and consumption of 3 kind of nutritional materials became more optimal after the treatment.Oxygen consumption per workload(Δ V· O 2/ΔW) and exercise ventilation oxygen consumption( V· O 2/W/V·E) were more decreased in Group A than those in Group B,with tensions of the respiratory muscle(PImax and PEmax) being more improved. Conclusions:Short term intravenous nutritional treatment can improve nutritional parameters,consumption of three kind of nutritional materials for energy and tension of the respiratory muscle.
Parenteral & Enteral Nutrition
Nutritional support Chronic obstructive pulmonary disease Energy metabolism Exercise intolerance