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促红细胞生成素治疗癌性贫血39例疗效观察 预览

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摘要 【目的】观察促红细胞生成素(EPO)治疗癌性贫血的疗效。【方法】选择77例癌性贫血患者,分为试验组(n=39),皮下注射EPO100U/(kg·次),每周3次,连续8周;对照组(n=38),8周内给予输血、补充铁剂以及更改放化疗方案。观察两组患者贫血、疲劳感、抑郁、活动耐力及睡眠等改善情况。【结果】试验组有效率为82.05%(32/39);试验组血红蛋白上升均值为(22.89±2.80)g/L高于对照组(12.00±5.06)g/L,差异有显著性(P〈0.01)。有79.49%(31/39)的患者疲劳感减轻,48.72%(19/39)的患者抑郁好转,35.90%(14/39)的患者活动耐力增加,38.46%(15/39)的患者睡眠改善。【结论】促红细胞生成素治疗癌性贫血可改善患者生存质量,减少输血需求。
出处 《医学临床研究》 CAS 2009年第6期 1063-1064,共2页 Journal of Clinical Research
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