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恶性肿瘤与Rh血型系统各表型的相关性分析 被引量:1

Correlation analysis between Rh blood group phenotypes and malignant tumors
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摘要 目的:分析恶性肿瘤患者Rh血型表型的分布特点,并与正常对照组进行比较,查找恶性肿瘤与Rh血型表型相关性。方法:对120例恶性肿瘤患者(患者组)及100例正常健康人群(对照组)进行Rh血型表型测定,对其表型分布进行统计分析,采用χ2检验和相对危险度OR值来估计相对危险性。结果:恶性肿瘤患者组与对照组Rh血型表型CcDEe分布之间的差异有统计学意义(χ2=4.51,P〈0.05)。恶性肿瘤患者组Rh血型表型分布从高到低分别是CcDEe54例(45.00%),CCDee39例(32.50%),CcDee14例(11.67%),ccDEE9例(7.50%),ccDEe3例(2.50%),CCDEe1例(0.83%);对照组Rh血型表型分布从高到低分别是CCDee47例(47.00%),CcDEe32例(32.00%),ccDEE9例(9.00%),CcDee6例(6.00%),ccDEe5例(5.00%),CCDEe1例(1.00%);结论:恶性肿瘤的发生与Rh血型表型的分布有关,CcDEe(OR=1.82)、CcDee(OR=2.07)表型发病率明显高于其他表型。 Objective:To investigate the correlation between Rh blood group phenotypes and malignant tumors.Method:Rh blood group phenotypes of 120 patients with malignant tumor and 100 healthy people were analyzed and analyzed by Chi-square test and relative risk OR value in order to estimate the relative risk. Rsullt:The distribution of Rh blood group phenotypes between patients and controls had a significant difference (χ2=4.51; P0.05). The Rh blood group phenotype distribution of patients from high to low in turn was as followings:CcDEe (54 case 45.00%),CCDee (39 case 32.50%),CcDee (14 case 11.67%),ccDEE (9 case 7.50%),ccDEe (3 case 2.50%) and CCDEe (1 case 0.83%). While in controls was CCDee (47 case 47.00%),CcDEe (32 case 32.00%),ccDEE (9 case 9.00%),CcDee (6 case 6.00%),ccDEe (5 case 5.00%) and CCDEe (1 case 1.00%). The persons who had Rh blood group phenotype of CcDEe (OR=1.82) and CcDee (OR=2.07) were liable to have tumors. Conclusion:There might be a certain correlation between malignant tumors and Rh blood group phenotype distribution,and the persons who had Rh blood group phenotype of CcDEe and CcDee were liable to have tumors.
作者 马现君 楚中华 曹秀玲 高海燕 李伟 孔燕 李德鲁 MA Xianjun CHU Zhonghua CAO Xiuling GAO Haiyan LI Wei KONG Yan LI Delu (1 Department of Blood Transfusion,Qilu Hospital of Shandong University,Jinan,250012,China;2 Department of Scientific Research,Qilu Hospital of Shandong University )
出处 《临床血液学杂志:输血与检验》 2010年第4期459-460,共2页 Journal of Clinical Hematology
基金 山东省教育厅课题(No:J08LH61) 山东省软科学研究计划项目(No:2009RKA062)
关键词 恶性肿瘤 Rh血型表型 相关性分析 malignant tumors Rh blood group phenotype correlation analysis
作者简介 通信作者:曹秀玲,E-mail:caoxiuling_69@yahoo.com.cn
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