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右美托咪啶于患者全麻状态下围拔管期血液动力学的影响 预览 被引量:10

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摘要 目的观察右美托味啶于全麻状态下围拔管期血流动力学的影响,尤其在用于合并Ⅰ、Ⅱ期高血压基础疾病患者全麻气管拔管的应用效果及安全性。方法患者150例,随机分为观察组(右美托咪啶组)和对照组(生理盐水组)各75例,比较两组患者在拔管前、拔管时、拔管后即刻、拔管后各时间段患者的心率、血压变化情况。结果(1)观察组各时段心率(HR)、收缩压(SBP)、舒张压(DBP)比较差异均无统计学意义(P〉0.05),对照组拔管时、拔管后即刻、拔管后5min及10min均有部分指标与拔管前差异有统计学意义(P〈0.05)。(2)观察组给予右美托咪啶静脉滴注后出现低血压1例,口干1例,不良反应均较轻微,停药后2d内均消失。结论患者处于围拔管期,其血流动力学方面会有较大波动,尤其在有基础高血压的患者更表现明显,右美托咪啶用于Ⅰ、Ⅱ期高血压患者全麻气管拔管可以起到稳定血流动力学作用,且临床用药安全性较高。 Objective Observe of the right Dexmedctomidine in anesthesia, tracheal extubation under the influence of hemodynamics.Methods 150 patients with Ⅰ、Ⅱ hypertension were selected and put into two groups as Dexmedetomidine group and saline group during Jan 2009 to Scp 2010 in our hospita, and before cxtubation,trachcal cxtubation,after cxtubation,aficr extubation,thc time heart rate, blood pressure changes wcrc observed.Results Heart rate observed group sessions (HR),systolic blood pressure (SBP),diastolic blood pressure (DBP) showed no significant difference (P〉0.05), the control group extubation, after extubation after cxtubation 5min and 10min before cxtubation were part of the index and significantly different (P〈0.05).Conclusion Dcxmcdetomidinc for stage Ⅰ、Ⅱ hypertension tracheal cxtubation can Play a role in stabilizing hemodynamics,and clinical drug safety is high;Blood dynamics;influence.
作者 傅羽龙 杨军良 程长秀 黄仁健 张云凤 FU Yu-long,YANG Jun-liang,CHENG Chang-xiu,HUANG Ren-jian,ZHANG Yun-feng (Longgang District center hospital of shenzhen,Shenzhen,Guangdong 518116,China)
出处 《湖南中医药大学学报》 CAS 2011年第6期 27-28,共2页 Journal of Traditional Chinese Medicine University of Hunan
关键词 右美托咪啶 高血压 全麻气管拔管 血液动力学 影响 Dcxmcdctomidine Hypcrtcnsion Trachcal cxtubation
作者简介 (作者简介)傅羽龙(1978-),男,江西永丰人,本科,主治医师,主要从事临床麻醉工作。
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  • 1刘继云 ,李荣胜 ,吴为玲 ,佘守章 ,张玉洁 ,杨美英 ,邓玲红 .舒芬太尼用于分娩镇痛的临床研究[J].中华妇产科杂志,2004,39(10):700-701. 被引量:108
  • 2邓立琴,丁风兰,刘红.全麻术后躁动225例分析[J].实用医学杂志,2006,22(2):165-167. 被引量:282
  • 3卫生部合理用药专家委员会.中国医师药师临床用药指南[M].重庆:重庆出版集团重庆出版社,2009:700-701. 被引量:376
  • 4Campistol JM,Sacks SH.Mechanisms of nephrotoxicity[J].Transplan tation,2006,69(3):555-560. 被引量:1
  • 5Scheinin B,Lindgren L,Randell T,et al.Dexmedetomidine attenu-ates sympathoadrenal responses to tracheal intubation and reduces the need for thiopentone and peroperative fentanyl[J].Br J Anaesth,1992,68(10):126-131. 被引量:1
  • 6Talke P,ChenR,ThomasB,et al.The hemodynamic and adrenergic effects ofperioperative dexmedetomidine infusion after vascular surgery[J].Anesth Analg,2000,90(7):834-839. 被引量:1
  • 7TaittonenMT,Kirvela OA,Aantaa R,et al.Effect of clonidine and dexmedetomidine premedication on perioperative oxygen consumption and haemodynamic state[J].Br J Anaesth,1997,78(2):400-406. 被引量:1
  • 8Khan ZP,Munday IT,JonesRM,et al.Effects of dexmedetomidine on isoflurane requirements in healthy volunteers.1:Pharmacodynamic and pharmacokinetic interactions[J].Br JAnaesth,1999,83(5):372-380. 被引量:1
  • 9Levanen J,MakelaML,ScheininH.Dexmedetomidine premedication attenuates ketamine-induced cardiostimulatory effects and postanes-thetic delirium[J].Anesthesiology,1995,82(12):1117-1125. 被引量:1
  • 10Peden CJ,Cloote AH,Stratford N,et al.The effect of intravenous dexmedetomidine premedication on the dose requirement of propofol to induce loss of consciousness in patients receiving alfentanil[J].An-aesthesia,2001,56(11):408-413. 被引量:1

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