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侧群细胞的研究进展

Research progress of side population cells
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摘要 在肿瘤的发生、发展中侧群细胞扮演着极其重要的作用。侧群细胞具有肿瘤干细胞的特性,尤其具备肿瘤的始发潜能,同时对化疗药物有较强的抵抗能力。对侧群细胞的生物学特性、分选与培养方法及侧群细胞与肿瘤耐药关系的研究,能为肿瘤的诊断和治疗提供新的思路和方法。 In the occurrence and development of tumors, side population cells play an extremely important role. They have the characteristics of cancer stem cells, especially their potential of tumor originating, and stronger drug-resistance. The study of biological characteristics, sorting and training methods of side population cells and the relationship between side population cells and tumor drug-resistance may shed some light on the diagnosis and treatment of cancer.
作者 李新星 王坚 LI Xin-xing, WANG Jian( Department of General Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China)
出处 《国际肿瘤学杂志》 CAS 2011年第8期579-582,共4页 Journal of International Oncology
基金 上海市科学技术委员会科研计划项目(09411960800)
关键词 肿瘤干细胞 活性氧 侧群细胞 Neoplastic stem cells Reactive oxygen species Side population cells
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参考文献15

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