Objective To evaluate the incidence of postanesthetic shivering in patients undergoing radical operation for lung cancer under dexmedetomidine-assisted anesthesia. Methods Eighty ASA Ⅰ or Ⅱpatients, aged 50-75 yr, height 158-180 cm, weighing 48-79 kg, scheduled for radical operation for lung cancer under general anesthesia combined with epidural anesthesia, were randomly divided into 2 groups （ n = 40 each） ： normal saline control group （group C） and dexmedetomidine group（ group D）. Anesthesia was induced with midazolam, fen- , propofol and rocuronium. The patients were tracheal intubated and mechanically ventilated. Anesthesia was maintained with sevoflurane inhalation and intermittent epidural ropivacaine. BIS was maintained at 40-55. Group D received dexmedetomidine intravenous infusion at 0.5 μg·kg-1·h-1 from immediately after tracheal intubation until 1 h before the end of operation, and group C received the equal volume of normal saline. The shivering within 1 h after operation was scored and recorded. Results The incidence rate of postanesthetic shivering was 50% in group C and 10% in group D. Compared with group C, the incidence rate and degree of shivering were decreased in group D（ P 〈 0.05）. Conclusion Dexmedetomidine-assistcd anesthesia can reduce the incidence of postanesthetic shivering in patients undergoing radical operation for lung cancer.
Chinese Journal of Anesthesilolgy