期刊文献+

原发性肝脏血管肉瘤的MRI表现与病理对照研究 预览 被引量:15

MRI Findings of Primary Hepatic Angiosarcoma: Correlation with Pathology
在线阅读 下载PDF
收藏 分享 导出
摘要 目的:观察原发性肝脏血管肉瘤(PHA)的MRI表现,分析其病理学基础,从而提高其诊断准确性。方法:回顾性分析4例PHA的MRI表现,评价病灶部位、大小、形态、信号特点及强化方式,并与病理对照观察。结果:4例PHA均为多发,具体表现为1枚较大主灶伴数目不等子灶,边界清晰,呈类圆形或分叶状。主灶呈不均匀T1WI低、T2WI高信号,病理上可见出血、坏死和纤维化;动脉期周边或中心明显强化,强化程度低于主动脉,3例可见中心杂乱血管影;门脉期及延迟扫描呈渐进性强化,但不能完全充填。3例伴有周边肝实质楔形或地图样灌注异常。子灶呈均匀T1WI低、T2WI高信号,增强后可无强化,也可呈向心性强化、均匀强化或中心强化。结论:PHA的MRI表现具有一定的特征性,常表现为多发肿块,易出血坏死,呈明显渐进性强化。 Purpose:To evaluate the MRI findings of primary hepatic angiosarcoma (PHA) and correlate with pathologic features. Methods: MR images of 4 PHA patients confirmed by histopathology were ret rospectively analyzed. The location, size, shape and dynamic enhancement pattern were evaluated. These findings were correlated with histopathology findings. Results: Four cases appeared as well de fined dominant masses with multiple satellite nodules. The dominant mass demonstrated lobular or round in shape and heterogeneous hypointensity at TlWI and markedly hyperintersity at T~ WI, which was as sociated with internal hemorrhage, necrosis and fibrosis at pathology. They all appeared as a flecked enhancement in the center or peripheral nodular enhancement during the arterial phase with lower en hancement degree than aortic artery. Chaotic central vascularization was present in 3 cases. In the portal venous and delayed phase, the enhanced areas of the mass were extended. Three cases demonstrateded phenomenon of hepatic perfusion disorders which appeared as map - like or wedge shape. The satellite lesions showed homogeneous hypo intensity at T1WI and markedly hyper - intersity at T2WI. They showed variable enhancement patterns, such as non enhancement, homogoneous, focal, rim - en- hancement or progressive opcification from periphery to center. Conclusion: MRI is an effective tech- nique for diagnosis of PHA. PHA often appears as multiple, well defined, hyper vascular lesions with progressive enhancement on serial post gadolinium images.
作者 李若坤 曾蒙苏 强金伟 饶圣祥 陈财忠 李新 纪元 LI Ruo kun, ZENG Meng su, QIANG Jin wei, RAO Sheng xiang, CHEN Cai zhong, LI Xin, JI Yuan
出处 《中国医学计算机成像杂志》 CSCD 北大核心 2011年第5期 420-424,共5页 Chinese Computed Medical Imaging
关键词 肝肿瘤 血管肉瘤 磁共振成像 病理学 Liver neoplasm Primary hepatic angiosarcoma Magnetic resonance imaging Pathology
作者简介 曾蒙苏 电子邮箱:zeng.mengsu@zs-hospital.sh.cn
  • 相关文献

参考文献18

  • 1Molina E,Hernandez A.Clinical manifestations of primary hepatic angiosarcoma.Dig Dis Sci,2003,48:677-682. 被引量:1
  • 2Locker GY,Doroshow JH,Zwelling LA,et al.The clinical features of hepatic angiosarcoma:a report of four cases and a review of the English literature.Medicine,1979,58:48-64. 被引量:1
  • 3Yu RS,Chen Y,Jiang B,et al.Primary hepatic sarcoma:CT findings.Eur Radiol,2008,18:2196-2205. 被引量:1
  • 4Chiu O,Frank JD,Dow CA.Hepatic angiosarcoma:detection with computed tomography.Australas Radiol,2005,49:163-165. 被引量:1
  • 5Koyama TK,Fletcher JG,Johnson CD,et al.Primary hepatic angiosarcoma:findings at CT and MR imaging.Radiology,2002,222:667-673. 被引量:1
  • 6梁玉梅,李向红,吕亚莉,钟梅.肝脏梭形细胞恶性肿瘤的临床病理及免疫组织化学特点[J].中华医学杂志,2005,85(2):96-100. 被引量:6
  • 7Park YS,Kim JH,Kim KW,et al.Primary hepatic angiosarcoma:imaging findings and palliative treatment with transcatheter arterial chemoembolization or embolization.Clinical Radiology,2009,64:779-785. 被引量:1
  • 8Maluf D,Cotterell A,Clark B,et al.Hepatic angiosarcoma and liver transplantation:case report and literature review.Transplant Proc,2005,37:2195-2199. 被引量:1
  • 9Kim HR,Rha SY,Cheon SH,et al.Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma.Ann Oncol,2009,20:780-787. 被引量:1
  • 10Drinkovic I,Brkljacic B.Two cases of lethal complications following ultrasound-guided percutaneous fine-needle biopsy of the liver.Cardiovasc Intervent Radiol,1996,19:360-363. 被引量:1

二级参考文献27

  • 1徐宏伟,晁明,王柏林,伍建军,孙继红.肝脏灌注异常的多层螺旋CT研究[J].实用放射学杂志,2004,20(6):512-515. 被引量:14
  • 2陈卉娇 ,张红英 ,李响 ,郭立新 ,魏兵 ,郭华 ,步宏 ,杨可 ,刘柏龄 .26例孤立性纤维性肿瘤临床病理及免疫组化特征[J].四川大学学报:医学版,2004,35(5):675-679. 被引量:44
  • 3田锦林,张金山.肝血管瘤周围灌注异常现象的CT探讨[J].中国医学影像技术,2006,22(7):1039-1042. 被引量:5
  • 4Washington K. Masses of the liver. In: Mills SE, ed. Sternberg's diagnostic surgical pathology. 4th ed. Philadephia: Lippingcott Williams & Wilkins, 2004. 1756-1761. 被引量:1
  • 5Mena H, Ribas JL, Pezeshkpour GH, et al. Hemangiopericytoma of the central nervous system: a review of 94 cases. Hum Pathol,1991,22: 84-91. 被引量:1
  • 6Louis DN, Paulus W, Haltia MJ. Haemangiopericytoma. In: Kleihues P, Cavenee WK, eds. WHO classification of tumors pathology & genetics tumors of the nervous system. Lyon: IARC Press, 2000. 190-192. 被引量:1
  • 7Haratake J, Horie A. An immunohistochemical study of sarcomatoid liver carcinomas. Cancer,1991, 68: 93-97. 被引量:1
  • 8Stocker JT, Ishak KG. Undifferentiated (embryonal) sarcoma of the liver: report of 31 cases. Cancer,1978,42:336-348. 被引量:1
  • 9DeMatteo RP, Shah A, Fong Y, et al. Results of hepatic resection for sarcoma metastatic to liver. Ann Surg,2001,234:540-548. 被引量:1
  • 10Nappi O, Ritter JH, Pettinato G, et al. Hemangiopericytoma: histopathological pattern or clinicopathologic entity? Semin Diagn Pathol,1995,12: 221-232. 被引量:1

共引文献11

同被引文献84

引证文献15

二级引证文献54

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈