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心房颤动合并冠心病患者抗栓治疗分析 预览 被引量:4

Analysis of atrial fibrillation in patients with coronary artery disease complicated with antithrombotic treatment
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摘要 目的观察心房颤动合并冠心病患者抗栓治疗方法。方法选择我院收治的心房颤动合并冠心病患者61例,随机分为两组A组阿司匹林联合氯吡格雷(31例);B组阿司匹林联合氯吡格雷联合华法林(30例),各组患者治疗观察12个月,分别随访分析患者出血事件和出血状况。结果 A治疗组5例(16.1%)发生脑栓塞,与B治疗组1例(3.3%)比较发生率差异具无统计学意义(P〉0.05)。严重出血发生率A治疗组4例(12.9%)与B治疗3例(10.0%)组比较差异无统计学意义(P〉0.05)。结论阿司匹林联合氯吡格雷与阿司匹林联合氯吡格雷联合华法林三重治疗心房颤动合并冠心病患者抗栓疗效及安全性相似。 Objective To observe of atrial fibrillation in patients with coronary artery disease complicated with antithrombotic treatment method.Methods In our hospital of atrial fibrillation in patients with coronary heart disease and 61 cases were randomly divided into two groups,group A aspirin plus clopodogrel(31 cases),group B aspirin plus clopidogrel combined with warfarin(30 cases),all patients were observed for 12 months,respectively,follow-up analysis in patients with hemorrhagic events and bleeding status.Results A treatment group of 5 cases(16.1%) the incidence of cerebral embolization,and B treatment group of 1 case(3.3%) to compare the incidence differences have statistical significance(P0.05).Severe bleeding incidence of A treatment group of 4 cases(12.9%) and B in the treatment of 3 cases(10%) were no significant difference(P0.05).Conclusion Aspirin plus clopidogrel in combination with warfarin in the treatment of atrial fibrillation in coronary heart disease patients complicated with antithrombotic efficacy and safety are similar.
作者 陈德容 黄晓玲 蒋军华 Chen De-yong,Huang Xiao-ling,JIANG Jun-hua.Chang'an Hospital in Dongguan,Guangdong 523843,China
出处 《中国现代药物应用》 2012年第8期 18-19,共2页
关键词 心房颤动 冠心病 抗栓治疗 Atrial fibrillation Coronary heart disease Antithrombotic therapy
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