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江苏省2011年健康人群脊髓灰质炎抗体水平监测分析 预览 被引量:13

Analysis of Polio Antibody Levels in Healthy Population in Jiangsu Province in 2011
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摘要 目的了解江苏省健康人群脊髓灰质炎一(简称“脊灰”)中和抗体水平,为及时制订免疫策略、维持无脊灰状态提供科学依据。方法采用随机抽样的方法抽取连云港、扬州两市健康人群,应用细胞中和实验法检测脊灰中和抗体。采用SPSS 18.0统计软件进行分析。结果在检测的736名健康人群的血清标本中,脊灰Ⅰ型、Ⅱ型和Ⅲ型抗体的阳性率分别为98.51%、98.37%和94.97%;几何平均滴度(GMT)分别为1:186.21、1:125.89和1:47.86;不同地区健康人群脊灰抗体阳性率和GMT无显著性差异;不同年龄段健康人群脊灰抗体阳性率有差异,抗体水平总趋势随着年龄增长而递减。结论江苏省健康人群脊灰抗体阳性率和GMT均保持在较高水平.已经形成了牢固的免疫屏障。 OBJECTIVE To understand the neutralized antibody level of the poliomyelitis among healthy in Jiangsu Province, and provide scientific evidence for 'the immunization strategy. METHODS The healthy people were randomly enrolled from Lianyungang and Yangzhou City. The poliomyelitis antibody level were detected by cells neutralization test. SPSS 18.0 software was used for statistical analysis. RESULTS The neutralizing antibody positive rates for polio Ⅰ , Ⅱ and Ⅲ were 98.51%, 98.37%, 94.97%, the geometric mean antibody titers(GMT) were 1:186.21,1:125.89, 1:47.86 respectively in 736 serum specimens.There were no significant differences in antibody levels between different regions. But the GMT were significantly associated with age, which was decreased with the age increasing. CONCLUSION The poliomyelitis antibody positive rates and GMT are still maintaining a high-level in Jiangsu. The firm immune protective barrier had been built against poliomyelitis among healthy people.
作者 吴昀 冷红英 叶珣 胡莹 邓秀英 陆培善 WU Yun, LENG Hong-ying, YE Xun, et al. Jiangsu Province Center for Disease Control and Prevention, Nanjing, 223002, China
出处 《中国初级卫生保健》 2012年第5期 76-77,共2页 Chinese Primary Health Care
关键词 脊髓灰质炎 中和抗体 健康人群 监测 poliomyelitis neutralized antibodies healthy people surveillance
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