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结核分枝杆菌中Pup-蛋白酶体系统和致病性之间的关系 被引量:7

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摘要 全世界约有1/3的人口感染结核分枝杆菌,每年有上百万人发病死亡[1]。目前结核病的诊断和治疗面临着巨大的挑战,尤其是活动性结核病以及耐药结核病的诊断及有效治疗问题。结核分枝杆菌本身的特点导致其和宿主之间的关系异常复杂,对其致病机制的认识依然不足。因此,对于结核分枝杆菌致病性和致病机制的研究是关键。
出处 《北京医学》 CAS 2012年第12期1068-1070,共3页 Beijing Medical Journal
基金 国家自然科学基金(No.31170064) 首都医学发展科研基金(2009-1055) 北京市优秀人才项目(No.2011D003034000013)
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