Objective To observe the therapy effect of levocarnitine in maintenance hemodialysis patients whose anemia have not reached the target value after the application of recombinant erythropoietin treatment six months. Methods Thirty-four cases of hemodialysis patients were randomly divided into 2 groups, 17 cases in each group. The two groups were given the application of recombinant erythropoietin 3 000 U, 2 times per week, subcutaneous injection. The treatment group were used levocarnitine 0.5 g, intravenous injection after each hemodialysis, control group were given intravenous saline. Treatment course was 12 weeks. Two groups of patients before and after treatment of red blood cell, hemoglobin, hematocrit, plasma albumin were observed. Results The treatment group patients erythrocyte, hemoglobin, hematocrit, plasma albumin increased level were higher than those of control group （P 〈 0.05）. Conclusion Levocamitine can significantly increase the effect of recombinant erythropoietin on anemia in hemodialysis patients, can improve the nutritional status of maintenance hemodialysis patients.
China Modern Medicine