Objective To explore the clinical effect of pantoprazole on the treatment ot pa- tients with duodenal ulcer and the related nursing measures. Methods 286 patients with duodenal ulcer were selected and randomly divided into control group and observation group, 143 cases in each group. Both groups were conducted with directed nursing intervention measures, and the control group was treated with conventional therapy while the observation group was treated with pantoprazole. Therapeutic effect, score of pain and score of negative emotions were compared between two groups. Results The therapeutic effect in the observation group was significantly better than the control group（P〈0. 05）; after treatment, the score of pain and score of negative emotions in the observation group were lower than the control group（P 〈 0.05）. Conclusion Application of panto- prazole and directed nursing intervention in the treatment of patients with duodenal ulcer can significantly improve the clinical therapeutic effect and relieve pain as well as the negative emotions.
Journal of Clinical Medicine in Practice