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无创通气治疗慢性阻塞性肺疾病合并肺性脑病的临床观察 预览 被引量:2

Clinical observation on noninvasive ventilation treat chronic obstructive pulmonary disease with pulmonary encephalopathy
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摘要 目的探讨无创通气对慢性阻塞性肺疾病急性加重期合并肺性脑病的治疗疗效。方法对33例肺性脑病患者使用无创通气治疗,并通过自身对照观察治疗前后血气分析指标的pH值、PaO2、PaCO2以及意识变化,判断疗效。结果33例患者中30例经无创通气治疗后临床症状改善,意识清醒,有效率达90.9%。治疗前后比较血气分析指标、pH值、PaO2均有明显升高,PaCO2明显下降,且具有显著差异(P〈0.05)。3例无效,改用有创通气治疗,失败率为9.1%。结论无创机械通气可以明显改善肺性脑病患者的临床症状和动脉血气分析的DH值、PaOz以及PaCO2;对慢性阻塞性肺疾病急性加重期合并肺性脑病患者是一种安全有效的治疗方法,值得在基层医院推广应用。 Objective To explore noninvasive ventilation therapy for chronic obstructive pulmonary disease with acute exacerbation of pulmonary encephalopathy.nethods Use of noninvasive ventilation therapy of 33 cases of patients with pulmonary encephalopathy and through their own contrast observation of the pH of the blood gas analysis indexes, PaO2, PaCO2, and change of consciousness before and after treatment,judging curative effect. Results A total of 30 cases of 33 patients after treatment with noninvasive ventilation in patients with clinical symptoms improve, conscious, the effective rate was 90.9% .Before and after treatment comparison of blood gas analysis index, pH, PaO2 were significantly elevated, PaCO2 declined obviously, and has significant difference (P 〈 0.05 and P 〈 0.01).3 cases of invalid, convert invasive ventilation therapy, the failure rate was 9.1%.Conclusion Noninvasive mechanical ventilation can obviously improve clinical symptoms of patients with pulmonary encephalopathy and the pH of arterial blood gas analysis, PaO2 and PaCO2. For chronic obstructive pulmonary disease in patients with acute aggravating period with pulmonary encephalopathy is a safe and effective treatment method, is worthy of popularization and application in basic hospital.
作者 黄国民 洪淑英 HUA NG Guomin1 HONG Shuying2 1. Department of Respiratory, the No.3 People's Hospital of Jingdezhen in Jiangxi Province, Jingdezhen 333001, China; 2.Department of Medical,the No.5 People' s Hospital of Jingdezhen in Jiangxi Province, Jingdezhen 333000, China
出处 《中国现代医生》 2013年第28期140-142,共3页
基金 江西省景德镇市科技项目(景科鉴字[2007]第13号)
关键词 慢性阻塞性肺疾病 肺性脑病 无创通气 Chronic obstructive pulmonary disease(COPD) Pulmonary encephalopathy Noninvasive ventilation
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