Objective To analyze the level of immunity against encephalitis B among healthy individuals and the prevalent trend of epidemic encephalitis B in Xianju county, so as to provide guidance for .IBE control. Methods Cluster random sampling was used in healthy population of the different age groups, different genders and different regions. Then double venous blood was collected respectively from the object of study in early and late epidemic pe- riod. IgG antibody against encephalitis B was detected by using ELISA. Results A total of 3741 healthy individu- als were monitored during 2005 - 2012 and the antibody positive rate of JE was 42.79%. The antibody positive rate of JE was 50.32% in the late＇ epidemic period, obviously higher than it in the early epidemic period （36.32%）. The difference showed statistical significance. The antibody positive rate among the people above 60 years old and under 15 years old in the late epidemic were both obviously higher than that in the early epidemic period. The differ- ence showed statistical significance. There was no significant difference among different age groups and different re- gions. Conclusion The viral antibody level among health people in Xianju Country is still low and it is important to vaccinate JE vaccine for them. High coverage and high quality of vaccination can effectively control the epidemic en- cephalitis B.
Chinses Journal of Health Laboratory Technology
Antibody against Encephalitis B