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江苏省人群麻疹免疫水平与发病率关系的研究 被引量:23

Relationship between measles immunization levels and the incidence among the populations in Jiangsu Province
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摘要 目的对江苏省健康人群麻疹抗体水平进行分析,以掌握江苏省健康人群麻疹发病的特点,了解人群免疫状况和水平,探索人群麻疹预防和控制措施。方法分年龄、分地区综合分析2009~2011年问淮安楚州、南京浦口、常州武进采集的健康人群麻疹抗体水平数据。结果本次监测样本累计共3435人,麻疹抗体阳性率为93.16%。1岁以下年龄组人群麻疹抗体阳性率较低,≥8月龄人群的阳性率均在90%以上。三地的麻疹抗体滴度三年中均有下降趋势,其中2009年淮安最高,几何均数为1970.90,2011年常州最低,为595.97。结论江苏省各地区、各年龄段人群麻疹抗体阳性率和抗体水平均处于正常范围内的波动状态。虽然历年来人群麻疹免疫水平略有下降,但人群免疫屏障较高,能有效遏制麻疹疫情。 Objective To analyze the immunization levels of measles among the healthy populations in Jiangsu Province, and grasp the epidemiological characteristics of measles and the seroprevalence of antibody to measles so as to explore the countermea- sures for preventing and controlling measles. Methods According to different ages and regions, we analyzed the data on mea- sles antibody levels among healthy populations in Chuzhou District of Huaian City, Pukou District of Nanjing City and Wnjin Dis- trict of Changzhou City from 2009 to 2011. Results A total of 3,435 serum samples were tested for measles antibody and the overall sero positive rate of measles antibody was 93.16%. The sero- positive rate of the group under 1 year of age was lower, wihiie the sero- positive rates of the groups aged ≥ 8 - month were all over 90%. The titers of antibody against measles vires in the three districts showed a downward trend in recent years, of which the anti measles virus antibody titer in the sera of vacein- ees in Huaian in 2009 was the highest (1,970.90) and the titer in the sera of vaccinees in Changzhou in 2011 was the lowest (595.97). Conclusions The sero - positive rate of measles antibody and measles antibody levels among different age popula- tions in different districts of Jiangsu Province fluctuate within the normal ranges. Though the titers of antibody against measles virus show a downward trend in recent years, the high prevalence of imnmnity to measles effectively decreases the incidence of measles.
作者 须凡帆 王旭雯 许祝平 刘元宝 马福宝 XU Fan - fan~, WANG Xu - wen, XU Zhu - ping, LIU Yuan - bao, MA Fu - bao Nanjing Medical University, Nanjing, Jiarzgsu 210029, China
出处 《实用预防医学》 CAS 2014年第1期41-43,共3页 Practical Preventive Medicine
基金 无锡市科技局指导性科研课题(CSZ00957、CSZ00N1124)
关键词 麻疹 免疫水平 发病率 Measles Immunization level Incidence rate
作者简介 须凡帆(1984-),女,江苏无锡人,硕士在读,医师,研究方向:免疫规划。 通讯作者:马福宝,E-mail:mfb0108@163.com。
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