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302例慢性阻塞性肺疾病急性加重期中医证候分型 被引量:66

TCM syndrome distribution in 302 patients with acute exacerbation of chronic obstructive pulmonary disease
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摘要 目的探讨慢性阻塞性肺疾病急性加重期的中医证候分型规律,为慢性阻塞性肺疾病急性加重期的中医临床治疗提供参考依据。方法检索1997至2012年中国知网(CNKI)所收录关于慢性阻塞性肺疾病急性加重期中医证候分型的相关文献,在此基础上制定慢性阻塞性肺疾病急性加重期患者中医证候信息采集表,并以此量表内的中医症状及体征作为调查条目,对302例患者进行数据采集。通过聚类分析和主成分分析对数据进行归类分析,从而归纳出慢性阻塞性肺疾病急性加重期的中医证候分型规律。结果慢性阻塞性肺疾病急性加重期的症状及体征通过聚类分析和主成分分析得到4个中医证型,分别为痰热壅肺、肺气上逆,肺肾气虚、外邪留恋,肺脾气虚、痰浊阻肺,脾肾气虚、气滞血瘀。结论通过运用聚类分析和主成分分析等数理统计方法研究慢性阻塞性肺疾病急性加重期中医证候分型,对促进本病中医证候分型标准化和规范化研究具有一定的参考价值。 Objective To study the distribution of TCM syndromes of acute exacerbation of chronic obstructive pulmonary disease (AECOPD), so as to provide reference for clinical therapy. Methods After searching literatures of TCM syndromes of AECOPD in CNKI from the year 1997 to 2012, TCM syndrome Scale composed of TCM symptoms was established. 302 patients with AECOPD were inquired according to the listed symptoms on the TCM syndrome Scale. All the symptoms arisen from the survey were analyzed by cluster analysis and principal component analysis. Results AECOPD consists of four TCM syndromes: phlegm-heat obstructing lung with lung qi ascending counterflow, qi deficiency of lung-kidney with exogenous pathogenic factors, qi deficiency of lung- spleen with turbid phlegm obstructing lung, qi deficiency of spleen-kidney with qi stagnation and blood stasis. Conclusion Application of cluster analysis and principal component analysis to TCM syndrome of AECOPD is valuable for standardization and normalization of syndrome classification.
作者 王胜 叶海勇 陈悦 季红燕 朱春冬 任薇 李春颖 周群 WANG Sheng , YE Hai-yong, CHEN Yue , JI Hong-yan, ZHU Chun-dong , REN Wei , LI Chun- ying, ZHOU Qun (1 Geratic Respiratory Department, the First Affiliated Hospital of Anhui University of TCM, Anhui 230031 ; 2 Zhejiang University of Traditional Chinese Medicine ; 3 Nanjing Panda Co. Community Health Service Center)
出处 《北京中医药大学学报》 CAS CSCD 北大核心 2015年第1期57-62,共6页 Journal of Beijing University of Traditional Chinese Medicine
基金 国家中医药管理局重点学科中医肺病学科开放基金资助项目(No.2011fbxk013B)
关键词 慢性阻塞性肺疾病 急性加重期 证候分型 聚类分析 主成分分析 chronic obstructive pulmonary disease acute exacerbation syndrome distribution clusteranalysis principal component analysis
作者简介 王胜,男,博士,主任医师,硕士生导师
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