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临床护理路径对提高结直肠癌患者FOLFOX化疗依从性的效果 预览 被引量:7

Clinical effect of clinical nursing pathway on improving the compliance of FOLFOX chemotherapy in patients with colorectal cancer
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摘要 目的 分析基于循证护理的临床护理路径在提高结直肠癌患者FOLFOX化疗依从性方面的临床效果.方法 将湖北省荆州中心医院胃肠外科2013年1月~2014年10月收治并接受FOLFOX化疗的80例结直肠癌患者作为研究对象,依据护理方法不同分为试验组和对照组,各40例.对照组接受传统整体护理;试验组在传统护理基础上,增加循证护理指导,以发现结直肠癌患者FOLFOX化疗目前存在的问题,找寻实证,制订临床护理路径,最后按照该路径进行护理干预.对比两组患者按期化疗率、化疗依从性、毒副反应发生情况和患者满意度.采用SPSS 22.0软件对结果进行统计学分析.结果 试验组患者的按期化疗率、化疗依从性和患者满意度高于对照组,组间差异有统计学意义(x2按期化疗=4.73,P<0.05;x2化疗依从性=5.28,P<0.05;x2满意度=9.36,P<0.05);试验组患者的消化道反应、口腔炎和外周神经毒性反应发生率低于对照组,差异有统计学意义(P<0.05).结论 与传统护理模式相比,基于循证护理的临床护理路径在结直肠癌患者FOLFOX化疗过程中可以提高患者依从性,保证化疗方案的顺利实施,取得良好的效果. Objective To analyze the clinical effect of evidence-based clinical nursing pathway on improving the compliance of FOLFOX chemotherapy in patients with colorectal cancer.Methods 80 cases of patients with colorectal cancer,who received the FOLFOX chemotherapy from January 2013 to October 2014 in Jingzhou Central Hospital,were divided into experiment group and control group,based on different nursing methods,each group had 40 cases.The control group received the traditional holistic nursing care,and the experiment group complied with traditional holistic nursing care as well as evidence-based clinical nursing pathway,including putting forward current problems existed in FOLFOX chemotherapy,seeking related evidence,working out clinical nursing pathway and putting it into practice.The chemotherapy on schedule,compliance of chemotherapy,toxicity reaction and satisfaction degree of patients were compared.The results were analyzed by SPSS 22.0 software.Results The chemotherapy on schedule,compliance of chemotherapy and satisfaction degree of patients in experiment group were better than those in control group (x2chemotherapy on schedule=4.73,P < 0.05;x2compliance=5.28,P < 0.05;x2satisfaction degree=9.36,P < 0.05).The rates of gastrointestinal reaction,stomatitis and peripheral nerve toxic reaction in experiment group were lower than those in control group (P < 0.05).Conclusion Compared with tradition holistic nursing care,the application of evidence-based clinical nursing pathway can improve the compliance of FOLFOX chemotherapy,smooth the chemotherapy regimens for patients with colorectal cancer,and acquire good effect.
作者 何瑷年 HE Ainian(Department of Stomach Enterochirurgia, Jingzhou Central Hospital, Hubei Province, Jingzhou 434020, China)
出处 《中国医药导报》 2015年第13期165-168,共4页 China Medical Herald
关键词 循证护理 临床护理路径 结直肠癌 FOLFOX化疗 依从性 Evidence-based nursing Clinical nursing pathway Colorectal cancer FOLFOX chemotherapy Compliance
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