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隐源性机化性肺炎24例临床分析 预览 被引量:7

Clinical analysis of 24 cryptogenic organizing pneumonia cases
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摘要 目的:探讨隐源性机化性肺炎的临床表现、病理特点和影像学特征,以提高临床诊断率和救治水平。方法:回顾分析24例经肺穿刺加病理确诊的隐源性机化性肺炎患者,对其临床表现、肺功能检查、影像学表现、组织病理学、治疗和转归进行综合分析。结果:24例隐源性机化性肺炎患者临床表现以发热、干咳、喘息、活动后呼吸困难和肺部湿啰音为主。肺功能显示阻塞性通气功能障碍12例、限制性通气功能障碍10例、混合性通气功能障碍2例。24例患者中23例肺泡灌洗液均以淋巴细胞为主,只有1例以中性粒细胞为主,肺CT以双肺多发磨玻璃影、多变性、反晕征为主。病理提示机化性肺炎表现。患者均接受糖皮质激素治疗,随访3~12个月,病情均好转。结论:隐源性机化性肺炎的临床表现和影像学表现缺乏特异性,确诊有赖于临床表现-影像-病理特征的综合诊断,一般预后良好,糖皮质激素治疗有效。 Objective:To explore the clinical manifestations,pathological features and imaging feature for the diagnosis of cryptogenic organizing pneumonia.Methods:A total of 24 eases of patients with cryptogenic orga- nizing pneumonia after lung biospy plus pathological diagnosis were retrospective analyzed,including clinical manifestations,pulmonary function tests,imaging,histopathology,treatment and outcome.Results: :The main clin- ical manifestations of 24 patients with cryptogenic organizing pneumonia were fever,dry cough,wheezing,dysp- nea and lung wet rales.Obstruetive,restrictive and mixed ventilation dysfunction was found in 12,10 and 2 patients.Lymphocytes in bronchoalveolar lavage fluid were found in 23 of 24 cases,and neutrophils was found only in one case.Pulmonary CT with multiple double pulmonary ground glass opacities,changeable and anti halo.Pathologic examination showed organizing pneumonia.Twenty-four patients received glucocorticoid therapy shown improvement during 3 to 12 months follow-up.Conclusion:The clinical and radiological manifestations of cryptogenic organizing pneumonia lack of specificity,the comprehensive diagnosis depends on the clinical manifestations,image and pathological features.The prognosis is benign and glucocorticoid treatment is effective.
作者 齐菲 苏宪灵 李玉柱 QI Fei,SU Xian-ling,LI Yu-zhu (Department of Respiratory Medicine,General Hospital of PEA,Beijing 100853,China)
出处 《中日友好医院学报》 2015年第4期211-213,F0002共4页 Journal of China-Japan Friendship Hospital
关键词 肺炎 隐源性机化性肺炎 肺穿刺术 活组织检查 糖皮质激素 pneumonia cryptogenic organizing pneumonia lung biopsy biopsy glucocorticoid
作者简介 齐菲(1980-),女,主治医师,医学硕士。 本文通讯作者。
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  • 1蔡后荣.间质性肺疾病的临床治疗进展[J].临床内科杂志,2005,22(4):223-226. 被引量:9
  • 2施举红,许文兵,刘鸿瑞,朱元珏,曹彬,陈勇,马毅,李单青.隐源性机化性肺炎18例的临床病理特征[J].中华结核和呼吸杂志,2006,29(3):167-170. 被引量:39
  • 3李惠萍,范峰,李秋红,赵兰,李霞,余慧,张容轩,易祥华,史景云,何国钧.肺活检证实隐源性机化性肺炎25例临床诊治体会[J].中华结核和呼吸杂志,2007,30(4):259-264. 被引量:73
  • 4American Thoracic Society, European Respiratory Society. American Thoraeie Society/European Respiratory Society International Multidisciplinary Consensus classification of the IdiopathicInterstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) Was adopted by the ATS board of directors,June 2001 and by the ERS Executive Committee,June 2001. Am J Respir Crit Care Med, 2002,165 : 277-304. 被引量:1
  • 5Davison AG, Heard BE, McAIlister WA, et al. Cryptogenic organizing pneumonltis. Q J Med, 1983,207 : 382-394. 被引量:1
  • 6Epler GR, Colby TV, McLoud TG, et al. Bronchilitis obliterans organizing pneumonia. N Engl J Med, 1985,312 : 152- 158. 被引量:1
  • 7Mueller-Mang C, Grosse C, Schmid K, et at. What every radiologist should know about idiopathic interstitial pneumonias. Radiographics, 2007,27 : 595 -615. 被引量:1
  • 8Drakopanagiotakis F, Polychronopoulos V, Judson MA. Organizing pneumonia. Am J Med Sci ,2008,335:34-39. 被引量:1
  • 9Gudmundsson G, Sveinsson O, lsaksson H J, et al. Epidemiology of" organizing pneumonia in Iceland. Thorax,2006,61 : 805-$08. 被引量:1
  • 10Cordier JF. Cryptogenic organizing pneumonia. Eur Respir J,2006, 28:422446. 被引量:1

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