OBJECTIVE To investigate clinical characteristics and related factors of vancomycin-induced Red man syndrome, and provide a reference for clinical use. METHODS Classification statistics were conducted on 20 cases of vancomycin-induced Red man syndrome reported in domestic medical journals from 1994 to 2014. RESULTS Vancomyein-induced Red man syndrome was independent of sex Children and adult people over age of 50 had a high incidence, which was possibly correlated with renal functions. The disease could occur during treatment course or after treatment. Most cases could he cured by discontinuing medication and symptomatic treatment. High concentrations might be a factor for vancomycin-indueed Red man syndrome. CONCLUSION Management on vaneo- mycin should be strengthened, characteristics of Red man syndrome understood, monitoring and focusing on prevention and treatment strengthened, to reduce occurrence of vancomycin-induced Red man syndrome.
Chinese Journal of Hospital Pharmacy
red man syndrome