期刊文献+

20例万古霉素致红人综合征国内文献分析 认领 被引量:14

Analysis of domestic literatures of vancomycin-induced red man syndrome in 20 cases
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摘要 目的:探讨万古霉素致红人综合征的临床特点及相关因素,为临床用药提供参考。方法:对1994—2014年国内医药期刊报道的20例使用万古霉素致红人综合征的病例进行分类统计。结果:万古霉素所致红人综合征与性别无关,多发于儿童和50岁以上人群,考虑与肾功能存在可能相关性。在用药过程中和用药后均可发生,停药并对症处理多可治愈。万古霉素用药浓度过高可能是引起红人综合征的因素。结论:应加强对万古霉素使用的管理,了解红人综合征易发特点,加强监测,重点防治,减少其发生。 OBJECTIVE To investigate clinical characteristics and related factors of vancomycin-induced Red man syndrome, and provide a reference for clinical use. METHODS Classification statistics were conducted on 20 cases of vancomycin-induced Red man syndrome reported in domestic medical journals from 1994 to 2014. RESULTS Vancomyein-induced Red man syndrome was independent of sex Children and adult people over age of 50 had a high incidence, which was possibly correlated with renal functions. The disease could occur during treatment course or after treatment. Most cases could he cured by discontinuing medication and symptomatic treatment. High concentrations might be a factor for vancomycin-indueed Red man syndrome. CONCLUSION Management on vaneo- mycin should be strengthened, characteristics of Red man syndrome understood, monitoring and focusing on prevention and treatment strengthened, to reduce occurrence of vancomycin-induced Red man syndrome.
作者 董艺宁 DONG Yi-ning (Shandong Huanghe Hospital, Shandong Jinan 250032, China)
机构地区 山东黄河医院
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2015年第16期1509-1511,共3页 Chinese Journal of Hospital Pharmacy
关键词 万古霉素 红人综合征 文献分析 vancomycin red man syndrome literature analysis
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参考文献14

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