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孕晚期睡眠呼吸暂停低通气综合征的影响因素 预览

The risk factors of sleep apnea and hyponea syndrome in the third trimester of pregnancy
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摘要 目的该研究拟通过病例-对照研究,讨论孕晚期睡眠呼吸暂停低通气综合征(SAHS)的影响因素。方法选取2013年2月-2014年2月在北京大学深圳医院产科就诊的36周以上、Hawaii打鼾量表≥2分的待产孕妇。在医院行8 h夜间睡眠呼吸初筛仪监测,根据呼吸暂停低通气指数(AHI)将患者随机分为SAHS组(n=31)与非SAHS组(n=91),比较两组孕妇各孕期的颈围、体重及胎儿体重等相关指标,分析孕晚期SAHS发生的危险因素。结果孕妇颈围每增加1 cm或孕前体重每下降2.5 kg/m2,AHI约上升3次/h。孕妇合并SAHS的主要影响因素是颈围(OR=3.373,95%可信区间1.784~6.377)及孕前体重(OR=0.640,95%可信区间0.460~0.891)。当颈围为37.25 cm时,诊断SAHS的敏感度为0.742,特异度为0.703。结论颈围、孕前体重与孕妇SAHS相关,对于颈围〉37.25 cm的孕妇,需筛查SAHS的可能性。 【Objective】A case-control study was designed to evaluate the attribute risk of sleep apnea and hyponea syndrome(SAHS).【Methods】Ante-partum women(Hawaii Snoring Scale ≥ 2)were enlisted during Feb.2013 and Feb.2014. Women underwent an overnight sleep monitor in hospital(22:00-6:00) and were divided according to apnea hyponea index(AHI) into 2 parts: 91 non-SAHS group and 31 SAHS group. The data of maternal neck circumference,weight and fetal growth were compared and the potential risk factors of SAHS in pregnancy were analyzed.【Results】Every time NC increased 1cm or pre-pregnancy BMI decreased 2.5kg/m2,AHI increased 3/h. The main risk factors of SAHS were NC(OR=3.373,95%CI 1.784~6.377) and pre-pregnancy BMI(OR=0.640,95%CI 0.460~0.891). The sensitivity of NC to predict SAHS was 0.742 and the specificity was 0.703.【Conclusion】SAHS in pregnancy was related with NC and pre-pregnancy BMI, SAHS should be evaluated when NC reached 37.25 cm.
作者 杨琳 何权瀛 郑绮雯 王娘娣 于兰芳 YANG Lin, HE Quan-ying, ZHENG Qi-wen, et al (Department of Health Medicine, Shenzhen Hospital Peking University, Shenzhen Guangdong 518036, P.R.China)
出处 《中国医学工程》 2015年第10期7-8,10共3页 China Medical Engineering
关键词 睡眠呼吸暂停低通气综合征 颈围 母体体重 sleep apnea and hyponea syndrome neck circumference maternal weight
作者简介 通信作者:何权瀛
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