期刊文献+

窦管交界和窦部直径对主动脉瓣关闭功能影响 预览 被引量:6

Effects of Diameters of Sinotubular Junction and Maximum Sinus on Aortic Valve Closure
在线阅读 下载PDF
收藏 分享 导出
摘要 为了探讨窦管交界和窦部直径对主动脉瓣关闭功能的影响,首先按照Labrosse提供的临床手术指导尺寸,建立基本的主动脉根部几何模型;改变窦管交界直径(分别为基本模型的1.2倍和0.8倍)、窦部直径(分别为基本模型的1.2倍和0.8倍)以及窦管交界直径和窦部直径(均为基本模型的1.2倍),共建立6组几何模型.窦部和瓣叶均施加0~10.665 kPa线性变化的压力负载,用计算机数值模拟的方法定量研究主动脉根部从接近关闭到完全关闭过程中,模型受到的最大应力数值和位置、瓣环直径变化以及对合区域面积比.计算结果表明:6组模型的主动脉根部最大应力值均出现在瓣叶和窦部接合位置,且最大应力值的范围是567~601 kPa,与Marom、Labrosse和Katayama的计算结果接近;窦管交界直径增大为基本模型的1.2倍时,瓣环直径扩大8.3%;6组模型的对合区域面积比计算结果相对变化不超过5%.结果表明:窦管交界变化比窦部直径变化对瓣环直径的影响大,而同样的主动脉根部结构,增大瓣环直径会减少瓣叶的有效对合,从而影响主动脉瓣关闭功能. The aim of present study was to determine the effects of diameters of sinotubular junction and maximum sinus on aortic valve closure function. The 3-dimensional geometry of a base aortic valve was reconstructed using the geometric constraints and modeling dimensions suggested by Labrosse,and then the diameters of sinotubular junction and maximum sinus were modified to create six geometric models with different dimensions. The models were simulated in a controlled situation which focused on the closing diastolic phase of the valve,starting with an almost closed valve. The pressure was raped from 0up to 10. 665 kPa. The performance of the aortic root was quantified in terms of value and position of maximum stress,annulus diameter as well as normalized ratio of cusp coaptation area. Results show that the maximum stress values occur at the connection between valve leaflets and sinuses for all models.Annulus diameter was increased 8. 3% with sinotubular junction diameter increased 1. 2 times. Relative changes of normalized cusp coaptation area were less than 5% for all six models. Compared with the maximum sinus diameter,sinotubular junction diameter has far more influence on annulus diameter,namely,on the function of aortic valve,because increasing the annulus diameter decreases the leaflet effective coaptation for the same aortic root.
作者 乔爱科 潘友联 董念国 QIAO Ai-ke;PAN You-lian;DONG Nian-guo;College of Life Science and Bio-engineering,Beijing University of Technology;Department of Cardiovascular Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology;
出处 《北京工业大学学报》 CAS CSCD 北大核心 2014年第5期776-780,共5页 Journal of Beijing Polytechnic University
基金 国家自然科学基金资助项目(81270297) 高等学校博士学科点专项科研基金资助项目(20111103110012) 北京市自然科学基金资助项目(KZ201210005006)
关键词 主动脉瓣 窦管交界直径 窦部直径 瓣环直径 对合区域面积比 aortic valve sinotubular junction diameter maximum sinus diameter annulus diameter normalized cusp coaptation area
  • 相关文献

参考文献13

  • 1.Valve Configuration Determines Long-Term Results After Repair of the Bicuspid Aortic Valve[J].Circulation.2011(2) 被引量:1
  • 2Michel R. Labrosse,Munir Boodhwani,Benjamin Sohmer,Carsten J. Beller.Modeling leaflet correction techniques in aortic valve repair: A finite element study[J].Journal of Biomechanics.2011(12) 被引量:1
  • 3Michel R. Labrosse,Keegan Lobo,Carsten J. Beller.Structural analysis of the natural aortic valve in dynamics: From unpressurized to physiologically loaded[J].Journal of Biomechanics.2010(10) 被引量:1
  • 4Tirone E. David,Manjula Maganti,Susan Armstrong.Aortic root aneurysm: Principles of repair and long-term follow-up[J].The Journal of Thoracic and Cardiovascular Surgery.2010(6) 被引量:1
  • 5Michel R. Labrosse,Carsten J. Beller,Francis Robicsek,Mano J. Thubrikar.Geometric modeling of functional trileaflet aortic valves: Development and clinical applications[J].Journal of Biomechanics.2005(14) 被引量:1
  • 6Susumu Katayama,Nobuyuki Umetani,Seiryo Sugiura,Toshiaki Hisada.The sinus of Valsalva relieves abnormal stress on aortic valve leaflets by facilitating smooth closure[J].The Journal of Thoracic and Cardiovascular Surgery.2008(6) 被引量:1
  • 7朱丹..主动脉根部形态、功能的研究及临床应用[D].复旦大学,2011:
  • 8.A fluid–structure interaction model of the aortic valve with coaptation and compliant aortic root[J].Medical & Biological Engineering & Computing.2012(2) 被引量:1
  • 9Dan Zhu,Qiang Zhao.Dynamic Normal Aortic Root Diameters: Implications for Aortic Root Reconstruction[J].The Annals of Thoracic Surgery.2011(2) 被引量:1
  • 10岳戈等编著..ADINA流体与流固耦合功能的高级应用[M].北京:人民交通出版社,2010:292.

同被引文献76

引证文献6

二级引证文献4

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈