期刊文献+

每日血液透析对尿毒症患者透析诱导期、血液生化指标及SCL-90评分的影响

Effect of daily hemodialysis on hemodialysis induction period, blood biochemical index and SCL-90 score in uremic patients
收藏 分享 导出
摘要 目的观察每日血液透析对尿毒症患者透析诱导期的临床效果以及对血液生化指标及SCL-90评分的影响。方法将我院肾病中心2015年1月—2018年1月新进入血液透析治疗室进行透析治疗的慢性肾衰竭尿毒症患者160例随机分配到观察组和对照组,每组各80例。对比两组患者临床效果的差异,及治疗前后尿素氮(BUN)、血肌酐(Scr)、血红蛋白(Hb)、总蛋白(TP)、白蛋白(ALB)、血钙、血氨比较,观察两组患者症状自评量表(symptom checklist 90,SCL90)中各指标对比。结果经2周治疗后,观察组心律失常、头痛、感染、消化道症状、肌肉痉挛发生率低于对照组(χ~2分别为3.274、4.475、2.485、4.348、7.585,P均<0.05),差异有统计学意义;皮肤瘙痒症状两组差异无统计学意义(χ~2=0.839,P>0.05);血液透析前1d,两组患者各项血液生化指标如BUN、Scr、Hb、TP、ALB、血钙、血氨差异无统计学意义(P>0.05);治疗2w后,尿素氮、血肌酐、血红蛋白、血钙、血氨指标明显改善,2组比较(P<0.05),但在总蛋白和白蛋白指标值方面,2组比较(P>0.05),治疗两周后,2组患者躯体及心理评分有差异,观察组效果更佳,差异有统计学意义(P<0.05)。结论每日血透疗法较传统血透疗法更有效,不良反应少,值得推广。 Objective Observation on clinical effect,blood biochemical index and SCL-90 score of daily hemodialysis in patients with uremia during dialysis-induced period.Methods A total of 160 patients with chronic renal failure uremia undertaken hemodialysis treatment during January 2015 to January 2018 were randomly assigned to the observation group and the control group,80 cases each.After the treatment,the difference of clinical outcomes between the two groups and the blood biochemical indexes before and after the treatment were compared.The indexes of SCL90 scale in the two groups were observed.Results After two weeks of dialysis,the incidence of arrhythmia,headache,infection,digestive tract symptoms and muscle spasm were lower in the observation group than in the control group(χ~2=3.274、4.475、2.485、4.348、7.585,P<0.05).However,there was no significant difference in this symptom between the two groups(χ~2=0.839,P>0.05).There was no significant difference in blood biochemical indexes in BUN,Cr,Hb,TP,ALB,blood calcium and blood ammonia before the hemodialysis in both groups(P>0.05).After two weeks of treatment,significant difference in the BUN,Cr,Hb,TP and ALB between the two groups was observed(P<0.05).There was no significant difference in blood calcium and ammonia(P>0.05).After 2 weeks of treatment observation group presented significantly improved SCL-90 scores.(P<0.05).Conclusion The daily hemodialysis therapy is more effective and less prone to adverse reactions than the traditional hemodialysis therapy in dialysis-induced period patients and thus may hold great clinical potentials.
作者 郭博慧 李向东 李毅 沈海燕 GUO Bohui;LI Xiangdong;LI Yi;SHEN Haiyan(Department of Nephrology,3201 Hospital,Xi'an Jiaotong University,Xi'an 723000,China)
出处 《中国输血杂志》 CAS 2019年第3期260-263,共4页 Chinese Journal of Blood Transfusion
关键词 血液透析 尿毒症 临床效果 血液生化指标 SCL-90 hemodialysis uremia clinical effect blood biochemical index SCL-90
作者简介 通信作者:李向东(1966.09-),男,本科,主任医师,研究领域:血液净化,慢性肾脏病,腹胱透析,电话18703834658,Email:320835236@qq.com
  • 相关文献

参考文献18

二级参考文献302

共引文献260

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈