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解溪穴穴位注射维生素B1对0级糖尿病足患者血浆TXB2、6-Keto-PGF1α的影响 预览 被引量:4

Effect of Jiexi Acupoint Injection of Vitamin B1 on 6-Keto-prostaglandin(6-Keto-PF1α) and Thromboxane B2_(TXB_2) of Level 0 Diabetic Foot Patients
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摘要 目的:探讨解溪穴穴位注射维生素B1对0级糖尿病足患者在接受治疗1月前后静脉血中6-酮-前列腺素F1α(6-Keto-PGF1α)、血栓素B2(TXB2)变化的影响,从而评估其疗效。方法:将90例患者随机分为3组,每组30例,分别为空白对照组、生理盐水注射组、维生素B1注射组。应用放免法分别测定3组患者在接受各自治疗方案1月前后静脉血中6-Keto-PGF1α、TXB2的数值。结果:空白对照组各项指标在治疗前后的变化无统计学意义(P〉0.05),而生理盐水组与维生素B1组各项指标在治疗前后的变化均具有统计学意义(P〈0.05),且维生素B1组与生理盐水组在治疗后的差异具有显著性(P〈0.05)。结论:解溪穴穴位注射维生素B1对0级糖尿病足患者血浆6-Keto-PGF1α、TXB2的影响确切,对于延缓糖尿病足的发展意义重大,值得推广。 Objective: To explore the effect on 6-Keto-prostaglandin( 6-Keto-PGF1α) and thromboxane B2( TXB2) in the blood of level 0 diabetic foot patients who received Jiexi( ST41) injection of Vitamin B1 treatment for one month,then to evaluate the curative effect.Methods: 90 patients were randomly divided into three groups,and each group had 30 patients.The first was the blank control group;the second was the normal saline injection group;the last was the Vitamin B1 injection group.The values of 6-Keto-PGF1αand TXB2 were measured by radioimmunoassay,then analyze whether the difference was statistically significant before and after treatment for one month.Results: The changes of 6-Keto-PGF1αand TXB2 in the blank control group before and after the treatment for one month were not statistically significant( P〉0.05),while the normal saline injection group and the Vitamin B1 injection group showed an obvious difference in the 6-Keto-PGF1αand TXB2changes( P〈0.05),and also between the normal saline injection group and the Vitamin B1 injection group,and the changes of 6-Keto-PGF1αand TXB2 were statistically significant after the treatment( P〈0.05).Conclusion: The effect on 6-keto-prostaglandin( 6-Keto-PGF1α) and thromboxane B2( TXB2) by Jiexi( ST41) injection of Vitamin B1 to level 0 diabetic foot patients is obvious,which has a significance for the delay of level 0diabetic foot development,and it is worth spreading.
作者 宋宏文 余白浪 周海旺 SONG Hong-wen,YU Bai-lang,ZHOU Hai-wang(Ezhou Hospital of Traditional Chinese Medicine ,Ezhou 436000, China)
机构地区 鄂州市中医院
出处 《针灸临床杂志》 2016年第1期32-34,共3页 Journal of Clinical Acupuncture and Moxibustion
关键词 解溪穴 穴位注射 维生素B1 糖尿病足 6-酮-前列腺素F1Α 血栓素B2 Jiexi acupoint Acupoint injection Vitamin B1 Diabetic foot 6-Keto-PGF1α) TXB2
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