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诺卡菌致角膜感染2例及文献复习 预览

Nocardia keratitis:Report of two cases and review of the literature
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摘要 目的加深对诺卡菌性角膜炎的认识,提高临床诊疗水平。方法分析2012年1月和2016年1月收治的2例诺卡菌性角膜炎病例的临床表现、实验室检查、诊治过程,并进行文献复习。结果该病临床表现无特异性,患者多伴有免疫功能低下及外伤史,诊断主要依据细菌学检查。结论诺卡菌性角膜炎是罕见的眼部疾病,其发病病程较长,易误诊,细菌培养和鉴定是诊断该病的金标准。早期找到病因及合理的用药是诊治该病的关键。 Objective To improve the diagnosis and treatment of the nocardia keratitis. Methods Two cases with nocardia keratitis were diagnosed in January 2012 and January 2016 respectively, the clinical features, laboratory manifestation and diagnosis and treatment process of the two cases were analyzed and the related literatures were reviewed.Results The disease was lack of specific clinical feature, also could be with low immune function and trauma history.The most precise diagnosis could be provided by bacteriology examination. Conclusion The nocardia keratitis is a rare eye disease,the disease course is long,easy to misdiagnosis. bacterial culture and identification is the gold standard for diagnosis of this disease.Early to find the cause of the disease and rational drug use is the key to the diagnosis and treatment of the disease.
作者 徐一 毛丽萍 顾云峰 王大选 陈鹏飞 郑美琴 XU Yi;MAO Liping;GU Yunfeng;WANG Daxuan;CHEN Pengfei;ZHENG Meiqin (Clinical Laboratory, the Eye Hospital of Wenzhou Medical University, Wenzhou 325000, China)
出处 《中国现代医生》 2016年第21期152-154,共3页
基金 浙江省自然科学基金资助项目(LY15H120003)
关键词 诺卡菌 感染 角膜炎 细菌培养 Nocardia Infection Keratitis Bacterial culture
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