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腹腔镜监护下宫腔镜诊治宫腔黏连及对炎症因子的影响 预览 被引量:2

Treatment of Intrauterine Adhesions and Its Influence on Inflammatory Factors Laparoscopic Care
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摘要 目的:总结腹腔镜监护下宫腔镜诊治宫腔黏连的治疗方法以及对相关炎症因子的影响。方法纳入96例各种原因引起的宫腔黏连患者,均行腹腔镜监护下宫腔镜子宫黏连切除术,判断宫腔黏连程度与月经异常的关系、宫腔黏连程度与手术史的关系,同时检测对比治疗前后2周患者血清肿瘤坏死因子α( TNF-α)和白介素6(IL-6)的表达水平。结果96例患者中治愈患者共52例,显效患者29例,无效患者共15例,临床总有效率为84.38%。其中有7例患者出现并发症,4例子宫穿孔,3例出血,经过适当处理后全部治愈。与治疗前对比,治疗2周后TNF-α和IL-6表达水平均明显降低,差异有显著性意义( P<0.05)。宫腔黏连程度与月经异常有关(χ^2=7.625,P<0.01)。宫腔黏连程度与手术史无关(χ^2=7.625,P>0.05)。结论宫腔镜诊治宫腔黏连是一种微创有效的方法,能够降低发病过程中的TNF-α、IL-2和IL-6表达水平,提高临床疗效。 Objective To summarize the laparoscopic treatment under the care treatment of intrauterine adhesions and their effects on inflammatory factors .Methods A total of 96 cases of intrauterine adhesions in patients with a variety of causes , underwent laparoscopic monitoring hysteroscopic resection of adhesions , intrauterine adhesions determine the relationship between the degree of menstrual abnormalities , intrauterine adhesions and surgery degree history of the rela-tionship , the simultaneous detection of comparing before and after 2 weeks of treatment in patients with serum tumor nec-rosis factor-α(TNF-α) and interleukin-6 (IL-6) expression levels.Results 96 patients were cured 52 cases of patients , 29 patients were cured , 15 cases of patients invalid , total effective rate was 84.38%.Including 7 patients with complications , 4 cases of uterine perforation , 3 cases of bleeding , after appropriate treatment cured .Comparison with be-fore treatment , after 2 weeks of treatment were significantly reduced TNF -αand IL-6 expression levels , the difference was significant (P〈0.05).Intrauterine adhesions degree of menstrual abnormalities (χ^2 =7.625,P〈0.01).Intrauter-ine adhesions surgery has nothing to do with the degree (χ^2 =7.625, P〉0.05).Conclusions The treatment of intrau-terine adhesions is a minimally invasive and effective method that can reduce the incidence during TNF -α, IL-2 and IL-6 expression levels, improve clinical efficacy.
作者 刘璐 LIU Lu( Department of Obstetrics and Gynecology ,Benxi Steel General Hospital,Benxi City ,Liaoning Province, 117000 )
出处 《航空航天医学杂志》 2016年第11期1355-1357,共3页 Aerospace Medicine
关键词 腹腔镜 宫腔镜 宫腔黏连 炎症因子 laparoscopy hysteroscopy intrauterine adhesions inflammatory cytokines
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新型冠状病毒肺炎防控与诊疗专栏