Objective To investigate the clinical value of detecting the serum uric acid in patients with essential hypertension. Methods 78 patients with essential hypertension in our hospital were selected as the observation group while 78 healthy people with physical examination and voluntary participants from our hospital over the same period were selected as the control group. Both of the two group were tested by uric acid oxidase method to detect the concentration of the serum uric acid and results of the two groups were compared. Results The blood uric acid levels in the observation group were significandy higher than those in the control group and the difference was significant （P 〈0.05） . There was statistical significance in the serum uric acid levels of different blood pressure levels and different complications of hypertension （P 〈0. 05）. Logistic regression analysis showed that age, serum uric acid and high TC were the risk factors of the essential hypertension, and HDL - C was the protective factor. Conclusion The increasing of serum uric acid levels is a major risk factor for the essential hypertension, which has significant application value in the clinical detection of the disease and can provide an important reference for disease diagnosis, treatment and prognosis.
Progress in Biomedical Engineering
serum uric acid，essential hypertension，clinical detection，application value