目的 评价自拟食疗方对改善肝硬化失代偿期患者营养状况的效果。方法 收集2014年10月至2015年11月于本院就诊的肝硬化失代偿期患者60例。根据治疗方法的不同,将患者分为试验组和对照组,每组30例。试验组患者在常规治疗的基础上增加营养小组为其提供的自拟食疗方进行营养干预;对照组给予常规肝硬化治疗。随访观察两组患者治疗前后握力、血清白蛋白（ALB）、前白蛋白（PA）及腹水严重程度的变化。结果 与治疗前相比,试验组患者接受食疗两个月后,握力、ALB及PA均显著提高,差异有统计学意义（t值分别为9.49、30.14和27.52,P均〈0.001）。治疗后,试验组患者的握力、ALB及PA均显著高于对照组,差异有统计学意义（t值分别为6.89、1.50和2.19,P均〈0.001）。治疗后,试验组无腹水及轻度腹水患者的比例显著高于对照组（P均〈0.05）。结论 自拟食疗方营养干预有助于改善肝硬化失代偿期患者的营养状况,可获得较理想的临床预后。
Objective To evaluate the effect of self-made diet formula on the improvement of nutritional status in patients with decompensated liver cirrhosis. Methods Total of 60 patients with decompensated liver cirrhosis treated in our hospital from October 2014 to November 2015 were enrolled and divided into experimental group and control group according to treatment method, 30 cases in each group. All patients received regular hepatoprotective therapy. Additionally, patients in experimental group were provided with self-made diet formula for nutrition intervention. The changes of grip, serum albumin （ALB）, prealbumin （PA） and ascites were observed before and after treatment in both groups. Results The levels of grip, ALB and PA increased significantly in experimental group after two months of therapy, the differences were statistically significant （t = 9.49, 30.14 and 27.52, P 〈 0.001）. After treatment, Grip, ALB and PA in experimental group were significantly higher than those in control group （t = 6.89, 1.50 and 2.19, P 〈 0.001）. The proportion of patients without ascites and with slight ascites were also significantly higher in experimental group than those in the control group after therapy （P 〈 0,05）. Conclusion Self-made diet formula is beneficial to improve the nutritional status and clinical prognosis of patients with decompensated liver cirrhosis.
Self-made diet formula
Liver cirrhosis, decompensated