期刊文献+

高氧液体在小儿单肺通气麻醉手术中应用的临床研究 预览 被引量:2

Curative efficacy of high oxygen liquid of one lung ventilation anesthesia in children
在线阅读 下载PDF
收藏 分享 导出
摘要 目的探讨高氧液体在小儿单肺通气麻醉手术中应用效果。方法选择2014年7月至2016年7月我院行麻醉手术的单肺通气患儿30例,均行肺叶切除术,通过随机数表法分为A组(n=15)和B组(n=15),A组患儿在单肺通气后通过30 ml(kg·h)的速度,恒速输入醋酸林格高氧液体,B组患儿用同样的速度输入等量的醋酸林格液体。比较两组患儿术中血气分析、炎性因子变化以及术后情况。结果两组患儿在T0(通气前)、T1(通气10 min)、T2(通气30 min)、T3(通气60 min)、T4(通气2 h)时,p H、动脉氧分压(PaO_2)、混合静脉血氧分压(PvO_2)、混合静脉血氧饱和度(PvO_2)水平均发生不同程度下降(P〈0.05),但A组在T1、T2、T3、T4时,pH、PaO_2、、水平均高于B组(P〈0.05);两组患儿T1、T2、T3、T4时肿瘤坏死因子(TNF)-α、白介素(IL)-6、IL-8、IL-10、丙二醛(MDA)水平较T0时比较,均出现不同程度的升高(P〈0.05);A组在T1、T2、T3、T4时,TNF-α、IL-6、IL-8、MDA均比B组低(P〈0.05);A组苏醒时间短于B组(P〈0.05),躁动发生率比B组低(P〈0.05)。结论在小儿麻醉手术行单肺通气后输注高氧液体,可有效预防低氧血症的发生,减轻炎性反应,安全性高,值得应用推广。 Objective To study curative efficacy of high oxygen liquid of one lung ventilation anesthesia in children. Methods 30 children of one lung ventilation anesthesia who received therapy from July2014 to July 2016 in our hospital were selected as research objects. According to random number table,all underwent pulmonary lobectomy,those children were divided into the A group( n = 15) and the B group( n =15). The A group after one lung ventilation,was treated with the 30 ml( kg·h) speed,constant speed input acetated glygoyle liquid oxygen,while the B group was treated with acetated ringer liquid injected the same speed.Then intraoperative blood gas analysis and inflammatory factor changesand postoperative conditions were compared. Results The p H,arterial oxygen partial pressure(PaO_2),mixed venous oxygen partial pressure(PvO_2) and mixed venous oxygen saturation(PvO_2) in the two groups were decreased in different degrees in T0( before ventilation),T1( ventilation 10 min),T2( ventilation 30 min),T3( ventilation 60 min),T4( ventilation 2 h)( P〈0.05),but the levels of p H,PaO_2,, in A group were higher than the B group in T1,T2,T3,T4( P〈0.05); the levels of tumor necrosis factor( TNF)-α,interleukin( IL)-6,IL-8,IL-10,malondialdehyde( MDA) in the T1,T2,T3,T4 compared with T0,were all increased in different degrees in the two groups( P〈0.05),but the level of TNF-α,IL-6,IL-8,MDA in A group were lower than B group in T1,T2,T3,T4( P〈0.05); the recovery time in A group was shorter than that the B group( P〈0. 05),the incidence rate of agitation was lower than the B group( P〈0.05). Conclusions The constant input of acetated high oxygen liquid is well for one lung ventilation anesthesia in children,which can preventing the occurrence ofhypoxia,reduce the inflammatory reaction,high security,it's worthy of application and promotion.
作者 田航 李新宇 黄俊祥 徐颖怡 谢观土 郭小花 宋兴荣 Tian Hang1 , Li Xinyu2, Huang Junxiang1 , Xu Yinyi1, Xie Guantu1 , Guo Xiaohua1, Song Xingrong1. (1.Anesthesiology Department, Guangzhou Women and Children Health Care Center, Guangzhou, 510623, China; 2Anesthesiology Department, The Second Hospital of Jilin University, Chuangchun, 130041, China)
出处 《中华肺部疾病杂志(电子版)》 CAS 2017年第1期41-45,共5页
基金 国家自然科学基金资助项目(81503172)
关键词 高氧液体 单肺通气 低氧血症 血气分析 炎性因子 High oxygen liquid One-lung ventilation Hypoxia Blood gas analysis Inflammatory factor
作者简介 通信作者:田航,Email:18902268146@139.com
  • 相关文献

参考文献9

二级参考文献117

共引文献35

同被引文献19

引证文献2

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈