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血栓弹力图与常规凝血四项分析凝血功能的一致性比较 预览 被引量:3

Comparison of Consistency of Thrombelastogram and Four Coagulation Indexes in Analyzing the Coagulation Function
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摘要 目的比较血栓弹力图(TEG)与常规凝血四项分析凝血功能的一致性。方法方便选取2016年3—10月在该院脑病科、糖尿病科、骨科、外科进行治疗的住院患者63例,行血栓弹力图、常规凝血四项检测及全血细胞分析血小板计数,并分析两种诊断方法的相关性和一致性。结果 TEG检测的凝血反应时间(R)与凝血酶原时间(PT)和活化部分凝血活酶时间(APTT)呈线性相关(r=0.229、0.249,P〈0.05);凝血形成时间(K)、凝块形成速率(Angle)、血栓最大振幅(MA)和纤维蛋白原(FIB)呈线性相关(r=0.457、0.583、0.656,P〈0.05);K、Angle、MA和血小板(Plt)呈线性相关(r=0.427、0.532、0.630,P〈0.05)。K、Angle、MA和FIB间存在一致性(Kappa=0.322、0.287、0.426,P〈0.05);K、Angle、MA和血小板计数(Plt)间存在一致性(Kappa=0.378、0.207、0.351,P〈0.05)。结论 TEG检测和常规凝血四项存在一定的相关性,一致性较弱,且两种方法无法相互替代。 Objective To compare the consistency of thrombelastogram and four coagulation indexes in analyzing the coagulation function.Methods 63 cases of inpatients in the department of cerebrosis,department of diabetes,department of orthopedics and department of surgery in our hospital from March to October 2016 were conveniently selected and both groups were tested by the thrombelastogram and four coagulation indexes,and the correlation and consistency of the two diagnostic method were analyzed.Results The clot reaction time R,prothrombin time PT and activated partial thromboplastin time APTT tested by TEG had an linear correlation(r=0.229,0.249,P〈0.05),and the clotting formation time K,clot formation rate Angle,thrombus maximum amplitude MA and contractinogen had a liner correlation(r=0.457,0.583,0.656,P〈0.05),K,Angle,MA and Platelet had a liner correlation(r=0.427,0.532,0.630,P〈0.05),and the K,Angle,MA were consistent with FIB(Kappa value =0.322,0.287,0.426,P〈0.05),and K,Angle,MA were consistent with platelet count Plt(Kappa value=0.378,0.207,0.351,P〈0.05).Conclusion TEG test has a certain correlation with the four coagulation indexes but the consistency is weak,and the two methods can't replace each other.
作者 王鸿雁 WANG Hong-yan(Department of Clinical Laboratory, Mentougou District Hospital of Traditional Chinese Medicine, Beijing, 102300 China)
出处 《中外医疗》 2017年第7期38-39,49共3页 Friend of Chemical Industry
关键词 血栓弹力图 常规凝血四项 凝血功能 一致性 Thrombelastogram Four coagulation indexes Coagulation function Consistency
作者简介 王鸿雁(1968-),女,北京人,本科,主管检验技师,研究方向:检验科.
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  • 1李道睿,张培彤,胡晓梅,杨宗艳,于明薇,林洪生.300例中晚期原发性支气管肺癌血瘀证分布规律的调查研究[J].中国中医药信息杂志,2007,14(3):19-21. 被引量:6
  • 2季鹏,顾春荣,卞智萍,陈相健,张寄南,杨笛.人心脏型脂肪酸结合蛋白的纯化与鉴定[J].中国组织工程研究与临床康复,2007,11(27):5387-5390. 被引量:3
  • 3中国肿瘤防治办公室 中国抗癌协会合编.中国常见恶性肿瘤诊治规范[M].北京:中国协和医科大学北京医科大学联合出版社,1991.1-13. 被引量:3
  • 4中华人民共和国卫生部医政司.常见恶性肿瘤诊治规范[M].北京:中国协和医科大学出版社,1999.773-781. 被引量:16
  • 5第七届全国血栓与止血学术会议制定的几项诊断参考标准.中华血液学杂志,2000.21:165-168. 被引量:5
  • 6Shmana P, Saxena R. A novel thromhoelastographic score to identify overt disseminated intravascular coagulation resulting in a hypocoagulable state [ J ]. Am J Clin Pathol, 2010, 134:97-102. 被引量:1
  • 7Craft RM, Chavez JJ, Snider CC, et al. Comparison of modified thrombelastograph and plateletworks whole blood assays to optical platelet aggregation for monitoring reversal of clopidogrel inhibition in elective surgery patients [ J]. J Lab Clin Med, 2005, 145: 309-315. 被引量:1
  • 8Slofstra SH, Spek CA, Ten H. Disseminated intravascular coagulation[ J]. Hematol, 2003, 4: 295-302. 被引量:1
  • 9Reikvam H, Steien E, Hauge B, et al. Thrombelastography [ J]. Transfus Apher Sci,2009, 40 : 119-123. 被引量:1
  • 10Weber AA, Adamzik M, Bachmann I-IS, et al. Methods to evaluate the pharmacology of oral antiplatelet drugs [J]. Herz, 2008, 33 : 287-296. 被引量:1

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