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2013—2016年河南省人民医院住院患者口服降糖药应用分析 预览 被引量:1

Analysis on Application of Oral Hypoglycemic Agents for Inpatients in Henan People's Hospital During 2013-2016
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摘要 目的:了解河南省人民医院(以下简称"我院")住院患者口服降糖药(oral hypoglycemic agents,OHA)的临床应用情况及发展趋势。方法:采用回顾性分析方法,对2013—2016年我院住院患者OHA的应用品种、销售金额、用药频度及限定日费用等进行统计分析。结果:2013—2016年我院住院患者OHA的销售金额分别为51.32、55.37、59.95、67.82万元,呈平稳增长趋势,2014、2015、2016年住院患者OHA的销售金额分别较上一年增长了7.89%、8.28%和13.12%,年均增长率为9.74%;2013—2016年我院住院患者OHA的DDDs分别为105 187、116 529、128 007、145 199,亦呈增长趋势,2014、2015、2016年住院患者OHA的DDDs分别较上一年增长了10.78%、9.85%和13.43%。4年来,DDDs排序均居前3位的口服降糖药为阿卡波糖、二甲双胍、格列齐特;二肽基肽酶-4抑制剂前景乐观,其销售金额年增长率居各类OHA之首;胰岛素增敏剂和非磺酰脲类促胰岛素分泌剂的市场份额显著下降。结论:我院住院患者OHA的应用情况基本合理。2型糖尿病患者需要长期甚至终身服用抗糖尿病药,因此,更加安全、有效、经济地使用OHA,使患者获益最大化,仍是值得每个临床工作者进一步深入研究的课题。 OBJECTIVE:To investigate the clinical application status and tendency of oral hypoglycemic agents (OHA) in Henan People' s Hospital( hereinafter referred to as "our hospital" ). METHODS : Statistical analysis was conducted on the application data of OHA during 2013-2016 in terms of categories, consumption sum, defined daily dose system (DDDs) and defined daily cost(DDC), etc. RESULTS: The consumption sum of OHA during 2013-2016 were respectively 513.2, 553.7, 599.5 and 678.2 thousand yuan, the consumption sum of inpatients with OHA were in an increasing tendency and respectively increased by 7. 89% , 8.28% and 13.12% during 2013-2016, the annual increasing rate was 9.74%. The DDDs of inpatients with OHA were respectively 105 187, 116 529, 128 007 and 145 199, which also were in an increasing tendency and respectively increased by 10. 78% , 9. 85% and 13.43%. Four tour years, the top three OHA ranked by DDDs were respectively acarbose, metformin and gliclazide. The DPP-4 inhibitor had a promising future, its increasing rate of consumption sum took the lead of the consumption sum of OHA. Yet the market share of insulin agonist and sulfonylurea insulinotropie agents decreasing significantly. CONCLUSIONS: The application of OHA in our hospital is basically rational. Patients with type-2 diabetes mellitus need to take OHA for a long time even life-long. Therefore, safe, effective and economical application of OHA and maximization of patients' benefits are still an essential task for the clinical staff to conduct the further research.
作者 王丽 张伟 WANG Li, ZHANG Wei (Dept. of Pharmacy, Henan People' s Hospital,Henan Zhengzhou 450000, China)
出处 《中国医院用药评价与分析》 2017年第3期388-390,共3页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 口服降糖药 销售金额 用药频度 限定日费用 用药分析 Oral hypoglycemic agents Consumption sum DDDs DDC Analysis of drug use
作者简介 药师。研究方向:医院药学。E-mail:xggwan@163.com 通信作者:主任药师。研究方向:医院药学。E-mail:zhangwei9001@126.com
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