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2013-2016年河南中医药大学第一附属医院门诊药房口服降糖药应用分析 预览 被引量:4

Analysis on Application of Oral Hypoglycemic Drugs in Outpatient Pharmacy of the First Affiliated Hospital of Henan University
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摘要 目的:了解河南中医药大学第一附属医院(以下简称“我院”)门诊药房口服降糖药的应用情况。方法:采用金额排序和限定日剂量分析方法,对2013—2016年我院门诊药房口服降糖药的品种、销售金额、用药频度和限定日费用等进行统计分析。结果:2013—2016年我院各类口服降糖药的销售金额相对稳定,其中α-葡萄糖苷酶抑制剂和磺酰脲类药物的销售金额各占近1/3的份额。4年来,二甲双胍的用药频度排序均居第1位;格列齐特用药频度增长较快,2015年其用药频度排序超过阿卡波糖,居第2位;格列奈类药物和新型降糖药二肽基肽酶-4抑制剂的使用量较小,噻唑烷二酮类药物的使用量最小。结论:我院门诊糖尿病患者对二甲双胍、格列齐特和阿卡波糖的选择倾向性较大,上述药物居主导地位,与《中国2型糖尿病指南》(2013版)的要求基本相符。格列奈类药物及新型降糖药二肽基肽酶-4抑制剂等未能得到广泛推广。 OBJECTIVE :To investigate the application status of oral hypoglycemic drugs in outpatient pharmacy of the First Affiliated Hospital of Henan University (hereinafter referred to as " our hospital") during 2013-2016. METHODS: Consumption sum ranking and defined daily dose system (DDDs) methods were adopted, statistical analysis was conducted on the application data of oral hypoglycemic drugs in terms of categories, consumption sum, DDDs and defined daily cost ( DDC), ect. RESULTS : The consumption sum of differet~t kinds of oral hypoglycemic drugs were stable during 2013-2016, among which the consumption sum of a-glucosidase inhibitor and sulfonylurea accounted almost 1/3. For four years, the medication frequence ranking of metformin took the lead. The medication frequence of gliclazide were in an increasing trend, the ranking of which dominated the second place and over acarbose in 2015. The consumption amount of glinides andnew antidiabetic drugs of DPP-4 were small, and TZDS drugs was the least. CONCLUSIONS : Metformin, gliclazide and acarbose play the leading role in outpatients of our hospital, and the selection of propensity in diabetics are larger, which is conform to Guide to Chinese Type 2 Diabetes (2013). Meanwhile, glinides and new antidiabetic drugs of DPP-4 are not widely applied.
作者 樊鑫 FAN Xin ( Dept. of Pharmacy, the First 450000, China) During 2013-2016 Affiliated Hospital of Henan University, Henan Zhengzhou
出处 《中国医院用药评价与分析》 2017年第4期537-539,542共4页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 口服降糖药 销售金额 用药频度 限定日费用 Oral hypoglyceInic drugs Consumption sum DDDs DDC
作者简介 主管药师。研究方向:医院药学。E-mail:357533358@qq.com
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