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分子印迹技术在农药残留检测中的应用进展 被引量:2

Progress of molecular imprinting technique on the determination of pesticides residues
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摘要 分子印迹技术是一种由模板、功能单体和交联剂制备的高分子功能材料以展示其选择性分子识别行为的技术,因为其具有专一识别性、预定性和实用性等特点,广泛应用于农药残留检测中。本文概括了分子印迹技术的基础理论、分子聚合物的制备以及该技术在农药残留检测中的应用,其中主要包括分子印迹在固相萃取、色谱固定相、固相微萃取、分子印迹膜和传感器等方面的应用,并对其发展趋势进行了展望。近几年,分子印迹技术与磁性分子、纳米材料、荧光分子、传感器等应用技术结合,期待在分子印迹固有特异性识别带来的高灵敏度基础上,实现快速检测技术的突破,解决现有农残速测仪所测农药品种受限、假阳性高、定量难等缺点,真正实现高通量快速痕量检测。 Molecular imprinting is a technique with the characteristic of selective molecular recognition, which is a kind of polymer-function material made of template, functional monomers and crosslinking agent. It is widely applied for detection of pesticide residues because of specificity recognition, predetermination and practicability. This paper summarized the basic theories and the preparation of molecular imprinting polymers, and reviewed its application in the determination of pesticides residues, such as solid phase extraction, stationary phase of chromatography, solid phase microextraction, molecular imprinted membrane, sensor and so on. Furthermore, the prospect was put forward. In recent years, with the development of molecular imprinting technology combining with magnetic molecules, nanomaterials, fluorescent molecules, sensors and other application technology, it is expected to achieve a breakthrough of rapid detection technology based on high sensitivity of molecular imprinting technology, to solve the existing shortcomings such as limited varieties of pesticide measure instruments, high false-positive and hard quantitative, and then truly achieve high-throughput rapid trace detection.
作者 杨霄鸿 贾明宏 杨天予 刘慧君 YANG Xiao-Hong1, 2, JIA Ming-Hong1, 2, YANG Tian-Yu2, LIU Hui-Jun1,2, 3 (1. Beijing Key Laboratory of Detection and Control of Spoilage Organisms and Pesticide Residues in Agricultural Products, Beijing University of Agriculture, Beijing 102206, China; 2.Food Science and Engineering College, Beijing University of Agriculture, Beijing 102206, China; 3.Beijing Laboratory for Food Quality and Safety, Beijing 102206, China)
出处 《食品安全质量检测学报》 CAS 2017年第2期462-467,共6页 Journal of Food Safety and Quality
基金 “提高人才培养质量建设项目”——北京市本科生研究训练项目(5045225076/006,5046516544/006)
关键词 分子印迹技术 农药残留 固相萃取 molecular imprinting technique pesticides residues solid phase extraction
作者简介 杨霄鸿,硕士,主要研究方向为食品质量安全。E-mail:xiaohong_yang@163.com 通讯作者:刘慧君,博士,中级职称,主要研究方向为食品质量安全检测与控制研究。E—mail:huijunliu78@163.com
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