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血必净注射液对脑卒中后重症吸入性肺炎的影响 预览

Therapeutic Effects of Xuebijing Injection on Stroke Patients with Serious Aspiration Pneumonia
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摘要 目的探讨血必净对脑卒中后重症吸入性肺炎临床效果的影响。方法选取2015年1月至2016年12月在我院呼吸科住院的脑卒中后重症吸入性肺炎64例,随机分成观察组和对照组各32例,两组均给予抗感染、吸氧、留置胃管及对症治疗,观察组加用血必净注射液50 m L加入生理盐水100 m L,每日静脉滴注2次,共14d,比较两组治疗后临床疗效和血氧饱和度(SaO2)、血氧分压(PaO2)、降钙素原(PCT)、C-反应蛋白(CRP)变化。结果观察组治疗后总有效率87.50%,显著高于对照组的62.50%(P〈0.05);与对照组相比观察组SaO2和PaO2显著提高,而PCT和CRP均明显下降(均P〈0.05)。结论在常规抗生素应用基础上加用血必净治疗,能进一步改善脑卒中后重症吸入性肺炎的临床疗效。 Objective To investigate the therapeutic effects of Xuebijing injection on stroke patients with serious aspiration pneumonia. Methods 64 cases of stroke patients with severe pneumonia were collected from January 2015 to December 2016 in our hospital, and randomly divided into observation group of 32 patients and control group of 32 patients. There were all given oxygen, anti-infection, indwelling gastric tube and symptomatic treatment, observation group was adding enteral 50 mL Xuebijing injection in normal saline 100 mL, daily intravenous infusion of 2 times, a total of 14 days. The blood oxygen saturation ( SaO2) , partial pressure of oxygen ( PaO2 ) , procalcitonin (PCT) , C-reactive protein (CRP) and clinical effect were detected in two groups after treatment. Results The total effective rate of observation group (87.50%) was significantly higher than that of control group(62.50% ) (P 〈 0.05). compared with control group, SaO2 and PaO2 significantly increased in observation group, but PCT and CRP decreased significantly in observation group (all P 〈 0.05). Conclusion On the basis of routine antibiotic application, Xuebijing injection could improve the clinical efficacy of stroke patients with serious aspiration pneumonia.
作者 吉瑜虹 李雪花 牛平 JI Yu-hong, LI Xue-hua, NIU Ping (Department of Respiration,Third Affiliated Hospital of Henan University of Science and Technology, Luoyang Dongfang Hospital, Luoyang 471003, China)
出处 《河南科技大学学报:医学版》 2017年第2期121-123,共3页 Journal of Henan University of Science & Technology:Medical Science
关键词 重症吸入性肺炎 脑卒中 血必净 Serious aspiration pneumonia stroke Xuebijing injection
作者简介 吉瑜虹(1964-),女,河南洛阳人,副主任医师,从事呼吸内科临床工作。
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